Rekombinanter Mesothelin (Amatuximab Biosimilar) Antikörper
Kurzübersicht für Rekombinanter Mesothelin (Amatuximab Biosimilar) Antikörper (ABIN7581566)
Target
Antikörpertyp
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
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Expressionssystem
- CHO Cells
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Verwendungszweck
- Anti-Mesothelin Reference Antibody (amatuximab)
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Sequenz
- QVQLQQSGPE LEKPGASVKI SCKASGYSFT GYTMNWVKQS HGKSLEWIGL ITPYNGASSY NQKFRGKATL TVDKSSSTAY MDLLSLTSED SAVYFCARGG YDGRGFDYWG SGTPVTVSSA STKGPSVFPL APSSKSTSGG TAALGCLVKD YFPEPVTVSW NSGALTSGVH TFPAVLQSSG LYSLSSVVTV PSSSLGTQTY ICNVNHKPSN TKVDKKVEPK SCDKTHTCPP CPAPELLGGP SVFLFPPKPK DTLMISRTPE VTCVVVDVSH EDPEVKFNWY VDGVEVHNAK TKPREEQYNS TYRVVSVLTV LHQDWLNGKE YKCKVSNKAL PAPIEKTISK AKGQPREPQV YTLPPSRDEL TKNQVSLTCL VKGFYPSDIA VEWESNGQPE NNYKTTPPVL DSDGSFFLYS KLTVDKSRWQ QGNVFSCSVM HEALHNHYTQ KSLSLSPGK,DIELTQSPAI MSASPGEKVT MTCSASSSVS YMHWYQQKSG TSPKRWIYDT SKLASGVPGR FSGSGSGNSY SLTISSVEAE DDATYYCQQW SKHPLTFGSG TKVEIKRTVA APSVFIFPPS DEQLKSGTAS VVCLLNNFYP REAKVQWKVD NALQSGNSQE SVTEQDSKDS TYSLSSTLTL SKADYEKHKV YACEVTHQGL SSPVTKSFNR GEC
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Produktmerkmale
- Anti-Mesothelin Reference Antibody (amatuximab) is expressed from CHO. The heavy chain type is huIgG1, and the light chain type is hukappa. It has a predicted MW of 145.5 kDa.
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Reinheit
- >95 %
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Isotyp
- IgG1
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Kommentare
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Therapeutic Agents by Target and Mechanism: MSLN inhibitors,ADCC
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Konzentration
- 1 mg/mL
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Buffer
- 25 mM histidine, 8 % sucrose, 0.01 % Tween80 pH 6.2
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Lagerung
- 4 °C,-80 °C
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Informationen zur Lagerung
- +4°C,-80°C
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- Mesothelin (Amatuximab Biosimilar)
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Substanzklasse
- Biosimilar
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Molekulargewicht
- 145.5 kDa
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UniProt
- Q13421
Target
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