PIKFYVE Antikörper
Kurzübersicht für PIKFYVE Antikörper (ABIN7581220)
Target
Alle PIKFYVE Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Verwendungszweck
- Rabbit polyclonal antibody to murine PIKfyve with reactivity to mouse/rat and human PIKfyve
-
Spezifität
- The PIKfyve antibody is directed at an N-terminal region of PIKfyve and detects mammalian forms of PIKfyve with an expected molecular weight of approximately 237 kDa.
-
Aufreinigung
- affinity purified using Protein A chromatography
-
Immunogen
- synthetic fusion peptide of aa 1-100
-
Isotyp
- IgG
-
-
-
-
Applikationshinweise
- IF/ICC – 2-5 ug/mL Western – 1.0 ug/mL Immunoprecipitation – 1.0 ug/mL Other in vitro and cellular applications are possible using this antibody, but have not been verified.
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Buffer
- PBS, pH 7.4
-
Lagerung
- 4 °C,-20 °C
-
Informationen zur Lagerung
- protect from direct light and store at 4°C for up to 30 days. For long term storage, aliquot and store at -80°C. Avoid repeated freeze/thaw cycles.
-
-
- PIKFYVE (phosphoinositide Kinase, FYVE Finger Containing (PIKFYVE))
-
Andere Bezeichnung
- PIKfyve
-
Hintergrund
- PIKfyve (aka PIP5K3) is an approximately 237 kDa lipid kinase enzyme. It is primarily found on early endosomes where it synthesizes PI(3,5)P2 from membrane-associated PI(3)P. Endosomal PIKfyve forms a complex with ArPIKfyve (Vac14) and Sac3 to regulate fusion, transport, and export of endosomes in the cell. PIKfyve also has protein kinase activity in the form of self-regulatory autophosphorylation.
-
Pathways
- Inositol Metabolic Process
Target
-