PIKFYVE Antikörper

Produktnummer ABIN7581220

Produktdetails anti-PIKFYVE Antikörper

Target: PIKFYVE (phosphoinositide Kinase, FYVE Finger Containing (PIKFYVE))

Reaktivität: Diverse Spezies

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PIKFYVE Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP), Immunocytochemistry (ICC)

Verwendungszweck: Rabbit polyclonal antibody to murine PIKfyve with reactivity to mouse/rat and human PIKfyve

Spezifität: The PIKfyve antibody is directed at an N-terminal region of PIKfyve and detects mammalian forms of PIKfyve with an expected molecular weight of approximately 237 kDa.

Aufreinigung: affinity purified using Protein A chromatography

Immunogen: synthetic fusion peptide of aa 1-100

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF/ICC – 2-5 ug/mL Western – 1.0 ug/mL Immunoprecipitation – 1.0 ug/mL Other in vitro and cellular applications are possible using this antibody, but have not been verified.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS, pH 7.4

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: protect from direct light and store at 4°C for up to 30 days. For long term storage, aliquot and store at -80°C. Avoid repeated freeze/thaw cycles.

Details zu PIKFYVE

Target: PIKFYVE (phosphoinositide Kinase, FYVE Finger Containing (PIKFYVE))

Andere Bezeichnung: PIKfyve (PIKFYVE Produkte)

Hintergrund: PIKfyve (aka PIP5K3) is an approximately 237 kDa lipid kinase enzyme. It is primarily found on early endosomes where it synthesizes PI(3,5)P2 from membrane-associated PI(3)P. Endosomal PIKfyve forms a complex with ArPIKfyve (Vac14) and Sac3 to regulate fusion, transport, and export of endosomes in the cell. PIKfyve also has protein kinase activity in the form of self-regulatory autophosphorylation.

Pathways: Inositol Metabolic Process