DGKZ Antikörper

Produktnummer ABIN7581194

Dieses Anti-DGKZ-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von DGKZ in WB. Geeignet für Human.

Kurzübersicht für DGKZ Antikörper (ABIN7581194)

Target: DGKZ (Diacylglycerol Kinase, zeta (DGKZ))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DGKZ Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-DGKZ Antikörper

Verwendungszweck: Rabbit polyclonal antibody against human diacylglycerol kinase zeta (DGKζ)

Kreuzreaktivität (Details): Shown to recognize a ~117kDa protein in wild-type DGK ζ protein with no cross activity to recombinant DGKα Protein.

Aufreinigung: Serum

Immunogen: peptide = LENRQHYQMIQREDQE

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB – 1:1000 Other in vitro and cellular applications are possible using this antibody, but have not been verified.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 0.01% thiomersal

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4 °C for up to 30 days. Aliquot and store at -20 °C if longer storage is necessary. Antibody is stable for at least 2 years when stored at -20 °C. Avoid repeated freeze/thaw cycles.

Details zu DGKZ

Target: DGKZ (Diacylglycerol Kinase, zeta (DGKZ))

Andere Bezeichnung: DGK Zeta

Hintergrund: DGK catalyzes a reaction terminating the protein kinase C (PKC)mediated signaling by converting diacylglycerol (DAG) to phosphatidic acid (PA), a signaling lipid which is involved in DNA synthesis, phospholipid synthesis, and regulation of several enzymes. DAG is an intermediate in phospholipid synthesis which functions as an allosteric activator of PKC. Research shows the zeta isoform of DGK undergoes tissue-specific alternative splicing resulting in an elongated N terminus enzyme predominantly in muscle.

Pathways: Myometrial Relaxation and Contraction