DLG4 Antikörper (AA 468-560) (Biotin)
Kurzübersicht für DLG4 Antikörper (AA 468-560) (Biotin) (ABIN725932)
Target
Alle DLG4 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Bindungsspezifität
- AA 468-560
-
Kreuzreaktivität
- Human, Affe, Maus, Ratte
-
Homologie
- Dog,Cow,Pig,Rabbit
-
Aufreinigung
- Purified by Protein A.
-
Immunogen
- KLH conjugated synthetic peptide derived from human PSD95
-
Isotyp
- IgG
-
-
-
-
Applikationshinweise
-
WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500 -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Konzentration
- 1 μg/μL
-
Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
-
Konservierungsmittel
- ProClin
-
Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- Store at -20°C for 12 months.
-
Haltbarkeit
- 12 months
-
-
- DLG4 (Discs, Large Homolog 4 (Drosophila) (DLG4))
-
Andere Bezeichnung
- PSD95
-
Hintergrund
-
Synonyms: PSD95, SAP9, SAP-9, Disks large homolog 4, Postsynaptic density protein 95, PSD-95, Synapse-associated protein 9, DLG4
Background: Interacts with the cytoplasmic tail of NMDA receptor subunits and shaker-type potassium channels. Required for synaptic plasticity associated with NMDA receptor signaling. Overexpression or depletion of DLG4 changes the ratio of excitatory to inhibitory synapses in hippocampal neurons. May reduce the amplitude of ASIC3 acid-evoked currents by retaining the channel intracellularly. May regulate the intracellular trafficking of ADR1B (By similarity).
-
Gen-ID
- 1742
-
UniProt
- P78352
-
Pathways
- Regulation of Muscle Cell Differentiation, Synaptic Membrane, Skeletal Muscle Fiber Development, Asymmetric Protein Localization, Regulation of long-term Neuronal Synaptic Plasticity
Target
-