NOS1 Antikörper (AA 51-150)

Produktnummer ABIN725585

Der Kaninchen Polyklonal Anti-NOS1-Antikörper wurde für WB, ELISA, IF (cc), IF (p), IHC (p) und IHC (fro) validiert. Er ist geeignet, NOS1 in Proben von Human, Ratte und Maus zu detektieren. Es sind 3+ Publikationen verfügbar.

Kurzübersicht für NOS1 Antikörper (AA 51-150) (ABIN725585)

Target: NOS1 (Nitric Oxide Synthase 1, Neuronal (NOS1))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NOS1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-NOS1 Antikörper

Bindungsspezifität: AA 51-150

Kreuzreaktivität: Human, Maus, Ratte

Homologie: Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human NOS-1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-NOS1 Antikörper (ABIN725585)

Zhu, Zhao, Luo, Li: "Gastrointestinal dysfunction in a Parkinson's disease rat model and the changes of dopaminergic, nitric oxidergic, and cholinergic neurotransmitters in myenteric plexus." in: Journal of molecular neuroscience : MN, Vol. 47, Issue 1, pp. 15-25, (2012) (PubMed).

Zhang, Liao, Ju, Song, Liu: "Neurochemical plasticity of nitric oxide synthase isoforms in neurogenic detrusor overactivity after spinal cord injury." in: Neurochemical research, Vol. 36, Issue 10, pp. 1903-9, (2011) (PubMed).

Wang, Yan, Zhao, Wu, Zhou: "The diversity of nNOS gene expression in avulsion-injured spinal motoneurons among laboratory rodents." in: Nitric oxide : biology and chemistry / official journal of the Nitric Oxide Society, Vol. 22, Issue 1, pp. 37-42, (2010) (PubMed).

Details zu NOS1

Target: NOS1 (Nitric Oxide Synthase 1, Neuronal (NOS1))

Andere Bezeichnung: nNos

Hintergrund:

Synonyms: NOS, bNOS, nNOS, IHPS1, N-NOS, NC-NOS, Nitric oxide synthase, brain, Constitutive NOS, NOS type I, Neuronal NOS, Peptidyl-cysteine S-nitrosylase NOS1, NOS1

Background: Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In the brain and peripheral nervous system, NO displays many properties of a neurotransmitter. Probably has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such SRR.

Gen-ID: 4842

UniProt: P29475

Pathways: Negative Regulation of Hormone Secretion, Myometrial Relaxation and Contraction