Calcitonin Receptor Antikörper (AA 31-120)

Produktnummer ABIN725330

Der Kaninchen Polyklonal Anti-Calcitonin Receptor-Antikörper wurde für ELISA, IF (cc), IF (p), ICC, IHC (p) und IHC (fro) validiert. Er ist geeignet, Calcitonin Receptor in Proben von Ratte und Maus zu detektieren. Es sind 4+ Publikationen verfügbar.

Kurzübersicht für Calcitonin Receptor Antikörper (AA 31-120) (ABIN725330)

Target: Calcitonin Receptor (CALCR)

Reaktivität: Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Calcitonin Receptor Antikörper ist unkonjugiert

Applikation: ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-Calcitonin Receptor Antikörper

Bindungsspezifität: AA 31-120

Kreuzreaktivität: Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from rat Calcitonin receptor

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-Calcitonin Receptor Antikörper (ABIN725330)

Tsukamoto, Menuki, Murai, Hatakeyama, Takada, Furukawa, Sakai: "Elcatonin prevents bone loss caused by skeletal unloading by inhibiting preosteoclast fusion through the unloading-induced high expression of calcitonin receptors in bone marrow cells." in: Bone, Vol. 85, pp. 70-80, (2016) (PubMed).

Su, Gu, Dong, Mei: "Ibuprofen rescues abnormalities in periodontal tissues in conditional presenilin 1 and presenilin 2 double knockout mice." in: International journal of molecular sciences, Vol. 14, Issue 9, pp. 18457-69, (2013) (PubMed).

Han, Ji, Wang, Yan, Wang, Luo, Mei, Su: "Abnormalities in periodontal and salivary tissues in conditional presenilin 1 and presenilin 2 double knockout mice." in: Molecular and cellular biochemistry, Vol. 347, Issue 1-2, pp. 13-20, (2011) (PubMed).

Details zu Calcitonin Receptor

Target: Calcitonin Receptor (CALCR)

Andere Bezeichnung: Calcitonin receptor

Hintergrund:

Synonyms: Calcitonin receptor, CT-R, C1A/C1B, Calcr

Background: This is a receptor for calcitonin. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. The calcitonin receptor is thought to couple to the heterotrimeric guanosine triphosphate-binding protein that is sensitive to cholera toxin.

Gen-ID: 116506

UniProt: P32214

Pathways: cAMP Metabolic Process