Calcitonin Receptor Antikörper (AA 31-120)

Produktnummer ABIN725330

Der Kaninchen Polyklonal Anti-Calcitonin Receptor Antikörper wurde für ELISA, IF (cc), IF (p), ICC, IHC (p) und IHC (fro) validiert. Er ist geeignet, Calcitonin Receptor in Proben von Ratte und Maus zu detektieren. Es sind 4+ Publikationen verfügbar.

Kurzübersicht für Calcitonin Receptor Antikörper (AA 31-120) (ABIN725330)

Target: Calcitonin Receptor (CALCR)

Reaktivität: Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Calcitonin Receptor Antikörper ist unkonjugiert

Applikation: ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-Calcitonin Receptor Antikörper

Bindungsspezifität: AA 31-120

Kreuzreaktivität: Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from rat Calcitonin receptor

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-Calcitonin Receptor Antikörper (ABIN725330)

Tsukamoto, Menuki, Murai, Hatakeyama, Takada, Furukawa, Sakai: "Elcatonin prevents bone loss caused by skeletal unloading by inhibiting preosteoclast fusion through the unloading-induced high expression of calcitonin receptors in bone marrow cells." in: Bone, Vol. 85, pp. 70-80, (2016) (PubMed).

Su, Gu, Dong, Mei: "Ibuprofen rescues abnormalities in periodontal tissues in conditional presenilin 1 and presenilin 2 double knockout mice." in: International journal of molecular sciences, Vol. 14, Issue 9, pp. 18457-69, (2013) (PubMed).

Han, Ji, Wang, Yan, Wang, Luo, Mei, Su: "Abnormalities in periodontal and salivary tissues in conditional presenilin 1 and presenilin 2 double knockout mice." in: Molecular and cellular biochemistry, Vol. 347, Issue 1-2, pp. 13-20, (2011) (PubMed).

Details zu Calcitonin Receptor

Target: Calcitonin Receptor (CALCR)

Andere Bezeichnung: Calcitonin receptor

Hintergrund:

Synonyms: Calcitonin receptor, CT-R, C1A/C1B, Calcr

Background: This is a receptor for calcitonin. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. The calcitonin receptor is thought to couple to the heterotrimeric guanosine triphosphate-binding protein that is sensitive to cholera toxin.

Gen-ID: 116506

UniProt: P32214

Pathways: cAMP Metabolic Process