CD16 Antikörper (Elab Fluor®Violet 610)
Kurzübersicht für CD16 Antikörper (Elab Fluor®Violet 610) (ABIN7566958)
Target
Alle CD16 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Verwendungszweck
- Elab Fluor®Violet 610 Anti-Human CD16 Antibody[3G8]
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Isotyp
- IgG1, kappa
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Applikationshinweise
- Each lot of this antibody is quality control tested by flow cytometric analysis. Applications vary, the appropriate dilutions must be determined for individual use.
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Kommentare
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Matching Isotype Control: E-AB-F09792T
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Buffer
- Phosphate buffered solution, pH 7.2, containing 0.09 % stabilizer and 1 % protein protectant.
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Lagerung
- 4 °C
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Informationen zur Lagerung
- This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
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Haltbarkeit
- 12 months
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- CD16
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Andere Bezeichnung
- CD16
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Hintergrund
- Fc gamma receptor,Fc gamma receptor 3,FcγRIII,CD16 is a 60 kD highly glycosylated protein. It is a member of the Ig superfamily and is also known as B7-1, B7, and Ly-53. CD16 is constitutively expressed on dendritic cells and monocytes/macrophages, and inducibly expressed on activated B and T cells. The ligation of CD28 on T cells with CD16 and CD86 (B7-2) on antigen presenting cells (such as dendritic cells, macrophages, and B cells) elicits co-stimulation of T cells resulting in enhanced cell activation, proliferation, and cytokine production. CD16 appears to be expressed later in the immune response than CD86. CD16 can also bind to CD152, also known as CTLA-4, to deliver an inhibitory signal to T cells.
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Gen-ID
- 941
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UniProt
- P08637, O75015
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Pathways
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
Target
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