SELPLG Antikörper (Elab Fluor®700)

Produktnummer ABIN7566723

Der Ratte Monoklonal Anti-SELPLG-Antikörper wurde für FACS validiert. Er ist geeignet, SELPLG in Proben von Maus zu detektieren.

Kurzübersicht für SELPLG Antikörper (Elab Fluor®700) (ABIN7566723)

Target: SELPLG (Selectin P Ligand (SELPLG))

Reaktivität: Maus

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser SELPLG Antikörper ist konjugiert mit Elab Fluor®700

Applikation: Flow Cytometry (FACS)

Klon: 4RA10

Produktdetails anti-SELPLG Antikörper (Elab Fluor®700)

Verwendungszweck: Elab Fluor®700 Anti-Mouse CD162 Antibody[4RA10]

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise: Each lot of this antibody is quality control tested by flow cytometric analysis. Applications vary, the appropriate dilutions must be determined for individual use.

Kommentare:

Matching Isotype Control: E-AB-F09822M1

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Phosphate buffered solution, pH 7.2, containing 0.09 % stabilizer and 1 % protein protectant.

Lagerung: 4 °C

Informationen zur Lagerung: This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

Haltbarkeit: 12 months

Details zu SELPLG

Target: SELPLG (Selectin P Ligand (SELPLG))

Andere Bezeichnung: CD162

Hintergrund: CD162,P-selectin glycoprotein ligand 1,PSGL-1,Selectin P ligand,Selplg,The 4RA10 antibody reacts with the N-terminal functional peptide of CD162 (P-selectin glycoprotein ligand-1, PSGL-1), encoded by the Selpl gene. PSGL-1 is expressed on the cell surface as a homodimer of approximately 230 kDa. In the mouse, Selpl mRNA is detected in most tissues, with high levels found in hematopoietic cells, brain, and adipose tissue. Flow cytometric analyses have revealed CD162 expression on bone marrow-derived mast and dendritic cells, splenic leukocytes, platelets, peripheral blood neutrophils, and neutrophil and T-cell lines. PSGL-1 is a ligand for P-selectin (CD62P) and is involved in leukocyte rolling, the migration of leukocytes into inflamed tissues, and responses to vascular injury. It is a sialomucin that must be specifically sialylated, fucosylated, and sulfated to bind P-selectin. There is also evidence that other ligands for PSGL-1 and CD62P may exist. 4RA10 mAb is reported to block the binding of mouse leukocytes to CD62P and CD62L.

Gen-ID: 20345

UniProt: Q62170