2B4 Antikörper (PE,Cy5)

Produktnummer ABIN7566585

Der PE,Cy5-konjugierte Maus Monoklonal anti-2B4 Antikörper (Klon C1-7) (ABIN7566585) detektiert spezifisch 2B4 in FACS. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für 2B4 Antikörper (PE,Cy5) (ABIN7566585)

Target: 2B4 (CD244) (Natural Killer Cell Receptor 2B4 (CD244))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser 2B4 Antikörper ist konjugiert mit PE,Cy5

Applikation: Flow Cytometry (FACS)

Klon: C1-7

Produktdetails anti-2B4 Antikörper (PE,Cy5)

Verwendungszweck: PE/Cyanine5 Anti-Human CD244 Antibody[C1.7]

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise: Each lot of this antibody is quality control tested by flow cytometric analysis. Applications vary, the appropriate dilutions must be determined for individual use.
FCM: 5 µL/test

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Phosphate buffered solution, pH 7.2, containing 0.09 % stabilizer and 1 % protein protectant.

Lagerung: 4 °C

Informationen zur Lagerung: This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

Haltbarkeit: 12 months

Details zu 2B4

Target: 2B4 (CD244) (Natural Killer Cell Receptor 2B4 (CD244))

Andere Bezeichnung: CD244

Hintergrund: 2B4,SLAMF4,CD244, known as 2B4, is a 38 kD type I transmembrane protein. It is a member of the CD2 subset of the immunoglobulin superfamily (IgSF) molecules. CD244 is expressed on NK cells, a subset of T cells (including most CD8+ T cells and γ/δ T cells), monocytes, basophils, and eosinophils. CD48 is the ligand of CD244. It has been reported that ligation of human CD244 results in enhanced NK cell cytotoxicity and cytokine production. Recent studies have shown that human CD244, like murine CD244, has both activating and inhibitory functions, which are dependent on the density of surface 2B4 expression, degree of ligation, and the level of the adaptor molecule SAP expression.

Gen-ID: 51744

UniProt: Q9BZW8