Rekombinanter CRP Antikörper

Produktnummer ABIN7566407

Der Human Monoklonal Anti-CRP-Antikörper wurde für WB und ELISA validiert. Er ist geeignet, CRP in Proben von Human zu detektieren.

Kurzübersicht für Rekombinanter CRP Antikörper (ABIN7566407)

Target: CRP (C-Reactive Protein (CRP))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Human

Klonalität: Monoklonal

Konjugat: Dieser CRP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Klon: SH1177-F3

Produktdetails anti-CRP Antikörper

Verwendungszweck: anti-CRP (human), mAb (rec.) (SH1177-F3)

Produktmerkmale:

Recombinant Antibody. Recognizes human C-reactive protein (CRP). Applications: ELISA, WB. Clone: SH1177-F3. Isotype: Human IgG1. Formulation: Liquid. In PBS. C-reactive protein (CRP) is a major cyclic, pentameric acute phase protein compound consisting of five identical, noncovalently bound, nonglycosylated subunits. CRP is produced by the liver, and its plasma levels rise dramatically during inflammatory processes occurring in the body. CRP is an initiator of classical complement cascade, binds to several nuclear components (chromatin, histones, etc.), plays an important role in innate immunity and mediates activities associated with pre-immune nonspecific host resistance. Specifically, there is a 100-1000 fold increase of CRP in response to injury, infection or inflammation. CRP is opsonic, an initiator of the classical complement cascade, and an activator of monocytes/macrophages. CRP also binds to several nuclear components including chromatin, histones and snRNP, suggesting that it may play a role as a scavenger during cell necrosis. CRP is involved in several host defense related functions based on its ability to recognize foreign pathogens and damaged cells of the host, and initiates pathogen elimination by interacting with humoral and cellular effector systems in the blood. Patients with elevated basal levels of CRP have been shown to be an increased risk for hypertension and cardiovascular disease.

C-reactive protein (CRP) is a major cyclic, pentameric acute phase protein compound consisting of five identical, noncovalently bound, nonglycosylated subunits. CRP is produced by the liver, and its plasma levels rise dramatically during inflammatory processes occurring in the body. CRP is an initiator of classical complement cascade, binds to several nuclear components (chromatin, histones, etc.), plays an important role in innate immunity and mediates activities associated with pre-immune nonspecific host resistance. Specifically, there is a 100-1000 fold increase of CRP in response to injury, infection or inflammation. CRP is opsonic, an initiator of the classical complement cascade, and an activator of monocytes/macrophages. CRP also binds to several nuclear components including chromatin, histones and snRNP, suggesting that it may play a role as a scavenger during cell necrosis. CRP is involved in several host defense related functions based on its ability to recognize foreign pathogens and damaged cells of the host, and initiates pathogen elimination by interacting with humoral and cellular effector systems in the blood. Patients with elevated basal levels of CRP have been shown to be an increased risk for hypertension and cardiovascular disease.

Aufreinigung: Purified

Reinheit: >95 % (SDS-PAGE)

Immunogen: Recombinant human C-reactive protein (CRP).

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: In PBS.

Handhabung: After opening, prepare aliquots and store at -20 °C.Avoid freeze/thaw cycles.Please handle under sterile conditions to avoid contamination.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung:

Stable for at least 1 year after receipt when stored at -20°C.

Stable for at least 1 week when stored at +4°C.

Details zu CRP

Target: CRP (C-Reactive Protein (CRP))

Andere Bezeichnung: CRP

UniProt: P02741

Pathways: Carbohydrate Homeostasis