CLIC1 Antikörper

Produktnummer ABIN7565990

Der Kaninchen Polyklonal Anti-CLIC1-Antikörper wurde für WB, ELISA und IP validiert. Er ist geeignet, CLIC1 in Proben von Human zu detektieren.

Kurzübersicht für CLIC1 Antikörper (ABIN7565990)

Target: CLIC1 (Chloride Intracellular Channel 1 (CLIC1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CLIC1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunoprecipitation (IP)

Produktdetails anti-CLIC1 Antikörper

Verwendungszweck: CLIC1 Antibody

Kreuzreaktivität (Details): This antibody is specific for human CLIC1.

Produktmerkmale: Synonyms: Rabbit Anti-CLIC1 Antibody, Chloride Intracellular Channel 1, Regulatory Nuclear Chloride Ion Channel Protein, Chloride Intracellular Channel Protein 1, Nuclear Chloride Ion Channel 27, Chloride Channel ABP, NCC27, HRNCC, G6, Nuclear Chloride Ion Channel Protein, RNCC Protein, P64CLCP

Aufreinigung: This product was Protein A purified from monospecific antiserum by chromatography.

Sterilität: Sterile filtered

Immunogen:

Immunogen: This protein-A purified antibody was prepared from whole rabbit serum produced by repeated immunizations with human CLIC1 recombinant protein.

Immunogen Type: Recombinant Protein

Anwendungsinformationen

Applikationshinweise: Application Note: Anti-CLIC1 has been tested in ELISA, Western Blot, and Immunoprecipitation. Expect a band at ~27kda in western blot using appropriate tissues and lysates. Positive controls used in western blot include CLIC1 overexpressing HEK293, WM-115, and HL-60 whole cell lysates. Western Blot Dilution: 1 μg/mL Immunoprecipitation Dilution: User Optimized ELISA Dilution: User Optimized

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.06 mg/mL

Buffer:

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Stabilizer: None

Preservative: 0.01 % (w/v) Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store vial at -20° C or below prior to opening. This vial contains a relatively low volume of reagent (25 μL). To minimize loss of volume dilute 1:10 by adding 225 μL of the buffer stated above directly to the vial. Recap, mix thoroughly and briefly centrifuge to collect the volume at the bottom of the vial. Use this intermediate dilution when calculating final dilutions as recommended below. Store the vial at -20°C or below after dilution. Avoid cycles of freezing and thawing.

Haltbarkeit: 12 months

Details zu CLIC1

Target: CLIC1 (Chloride Intracellular Channel 1 (CLIC1))

Andere Bezeichnung: CLIC1

Hintergrund: Background: CLIC1 (Chloride Intracellular Channel 1) can insert into membranes and form chloride ion channels. Chloride channels are a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH , and regulation of cell volume. Chloride intracellular channel 1 is a member of the p64 family, the protein localizes principally to the cell nucleus and exhibits both nuclear and plasma membrane chloride ion channel activity. This channel activity depends on the pH . Membrane insertion seems to be redox-regulated and may occur only under oxydizing conditions. Involved in regulation of the cell cycle. Anti-CLIC1 is useful for researchers interested in Blackwater Fever and Penicilliosis diseases, along with Cancer, Neuroscience, and activation of cAMP-Dependent PKA.

Gen-ID: 1192

NCBI Accession: NP_001274522

UniProt: O00299