ORM1 Antikörper (HRP)
Kurzübersicht für ORM1 Antikörper (HRP) (ABIN7565737)
Target
Alle ORM1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Verwendungszweck
 - Alpha-1-Acid Glycoprotein Antibody Peroxidase Conjugated
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Kreuzreaktivität (Details)
 - Assay by immunoelectrophoresis resulted in a single precipitin arc against anti-Peroxidase, anti-Rabbit Serum as well as purified and partially purified a-1-Acid Glycoprotein [Human Plasma].
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Produktmerkmale
 - Synonyms: rabbit anti-Alpha-1-Acid Glycoprotein Antibody Peroxidase Conjugation, HRP conjugated rabbit anti-Alpha-1-Acid Glycoprotein 1 Antibody, AGP1, AGP 1, OMD 1, OMD1, Orosomucoid-1
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Aufreinigung
 - Anti-Alpha-1-Acid Glycoprotein Antibody is an IgG fraction antibody purified from monospecific antiserum by a multi-step process which includes delipidation, salt fractionation and ion exchange chromatography followed by extensive dialysis against the buffer stated above.
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Sterilität
 - Sterile filtered
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Immunogen
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Immunogen: a-1-Acid Glycoprotein [Human Plasma]
Immunogen Type: Native Protein
 
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Applikationshinweise
 - Application Note: Anti-Alpha-1-Acid Glycoprotein peroxidase Antibody has been tested by ELISA and dot blot and is suitable for Western Blot and Immunohistochemistry. Specific conditions for reactivity should be optimized by the end user. Immunohistochemistry Dilution: 1:500 - 1:2,500 Western Blot Dilution: 1:1,000 - 1:5,000 ELISA Dilution: 1:15,000 Other: User Optimized
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Beschränkungen
 - Nur für Forschungszwecke einsetzbar
 
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Format
 - Liquid
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Konzentration
 - 1.0 mg/mL
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Buffer
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Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: 10 mg/mL Bovine Serum Albumin (BSA) - Immunoglobulin and Protease free
Preservative: 0.01 % (w/v) Gentamicin Sulfate. Do NOT add Sodium Azide! - 
                                            
Konservierungsmittel
 - Sodium azide
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Vorsichtsmaßnahmen
 - This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
 - -20 °C
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Informationen zur Lagerung
 - Store vial at -20° C or below prior to opening. This vial contains a relatively low volume of reagent (25 μL). To minimize loss of volume dilute 1:10 by adding 225 μL of the buffer stated above directly to the vial. Recap, mix thoroughly and briefly centrifuge to collect the volume at the bottom of the vial. Use this intermediate dilution when calculating final dilutions as recommended below. Store the vial at -20°C or below after dilution. Avoid cycles of freezing and thawing.
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Haltbarkeit
 - 12 months
 
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- ORM1 (Orosomucoid 1 (ORM1))
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Andere Bezeichnung
 - ORM1
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Hintergrund
 - Background: Alpha-1-Acid Glycoprotein Antibody detects alpha-1-acid glycoprotein (AGP or AAG. ) Alpha-1-acid glycoprotein is an acute phase (acute phase protein) plasma alpha-globulin glycoprotein and is modulated by two polymorphic genes. It is synthesized primarily in hepatocytes and has a normal plasma concentration between 0.6-1.2 mg/mL (1-3 % plasma protein).[1] Plasma levels are affected by pregnancy, certain drugs, and certain diseases, particularly HIV. The only established function of ORM is to act as a carrier of basic and neutrally charged lipophilic compounds. In medicine, it is known as the primary carrier of basic drugs (whereas albumin carries acidic drugs), steroids, and protease inhibitors. Aging causes a small decrease in plasma albumin levels, if anything, there is a small increase in α1 acid glycoprotein. The effect of these changes on drug protein binding and drug delivery, however, appear to be minimal. Anti-Alpha-1-Acid Glycoprotein Antibody is ideal for investigators involved in infectious disease and cell cycle protein research.
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Gen-ID
 - 5004
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NCBI Accession
 - NP_000598
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UniProt
 - P02763
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Pathways
 - Response to Growth Hormone Stimulus
 
Target
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