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ORM1 Antikörper (HRP)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch ORM1 in WB, IHC, ELISA und DB. Er zeigt eine Reaktivität gegenüber Human.
Produktnummer ABIN7565737

Kurzübersicht für ORM1 Antikörper (HRP) (ABIN7565737)

Target

Alle ORM1 Antikörper anzeigen
ORM1 (Orosomucoid 1 (ORM1))

Reaktivität

  • 77
  • 35
  • 21
  • 5
  • 5
  • 4
Human

Wirt

  • 89
  • 34
  • 3
  • 2
  • 2
  • 1
  • 1
Kaninchen

Klonalität

  • 95
  • 37
Polyklonal

Konjugat

  • 84
  • 19
  • 8
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser ORM1 Antikörper ist konjugiert mit HRP

Applikation

  • 100
  • 76
  • 45
  • 42
  • 30
  • 13
  • 13
  • 9
  • 7
  • 6
  • 4
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Dot Blot (DB)
  • Verwendungszweck

    Alpha-1-Acid Glycoprotein Antibody Peroxidase Conjugated

    Kreuzreaktivität (Details)

    Assay by immunoelectrophoresis resulted in a single precipitin arc against anti-Peroxidase, anti-Rabbit Serum as well as purified and partially purified a-1-Acid Glycoprotein [Human Plasma].

    Produktmerkmale

    Synonyms: rabbit anti-Alpha-1-Acid Glycoprotein Antibody Peroxidase Conjugation, HRP conjugated rabbit anti-Alpha-1-Acid Glycoprotein 1 Antibody, AGP1, AGP 1, OMD 1, OMD1, Orosomucoid-1

    Aufreinigung

    Anti-Alpha-1-Acid Glycoprotein Antibody is an IgG fraction antibody purified from monospecific antiserum by a multi-step process which includes delipidation, salt fractionation and ion exchange chromatography followed by extensive dialysis against the buffer stated above.

    Sterilität

    Sterile filtered

    Immunogen

    Immunogen: a-1-Acid Glycoprotein [Human Plasma]

    Immunogen Type: Native Protein

  • Applikationshinweise

    Application Note: Anti-Alpha-1-Acid Glycoprotein peroxidase Antibody has been tested by ELISA and dot blot and is suitable for Western Blot and Immunohistochemistry. Specific conditions for reactivity should be optimized by the end user. Immunohistochemistry Dilution: 1:500 - 1:2,500 Western Blot Dilution: 1:1,000 - 1:5,000 ELISA Dilution: 1:15,000 Other: User Optimized

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1.0 mg/mL

    Buffer

    Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

    Stabilizer: 10 mg/mL Bovine Serum Albumin (BSA) - Immunoglobulin and Protease free

    Preservative: 0.01 % (w/v) Gentamicin Sulfate. Do NOT add Sodium Azide!

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store vial at -20° C or below prior to opening. This vial contains a relatively low volume of reagent (25 μL). To minimize loss of volume dilute 1:10 by adding 225 μL of the buffer stated above directly to the vial. Recap, mix thoroughly and briefly centrifuge to collect the volume at the bottom of the vial. Use this intermediate dilution when calculating final dilutions as recommended below. Store the vial at -20°C or below after dilution. Avoid cycles of freezing and thawing.

    Haltbarkeit

    12 months
  • Target

    ORM1 (Orosomucoid 1 (ORM1))

    Andere Bezeichnung

    ORM1

    Hintergrund

    Background: Alpha-1-Acid Glycoprotein Antibody detects alpha-1-acid glycoprotein (AGP or AAG. ) Alpha-1-acid glycoprotein is an acute phase (acute phase protein) plasma alpha-globulin glycoprotein and is modulated by two polymorphic genes. It is synthesized primarily in hepatocytes and has a normal plasma concentration between 0.6-1.2 mg/mL (1-3 % plasma protein).[1] Plasma levels are affected by pregnancy, certain drugs, and certain diseases, particularly HIV. The only established function of ORM is to act as a carrier of basic and neutrally charged lipophilic compounds. In medicine, it is known as the primary carrier of basic drugs (whereas albumin carries acidic drugs), steroids, and protease inhibitors. Aging causes a small decrease in plasma albumin levels, if anything, there is a small increase in α1 acid glycoprotein. The effect of these changes on drug protein binding and drug delivery, however, appear to be minimal. Anti-Alpha-1-Acid Glycoprotein Antibody is ideal for investigators involved in infectious disease and cell cycle protein research.

    Gen-ID

    5004

    NCBI Accession

    NP_000598

    UniProt

    P02763

    Pathways

    Response to Growth Hormone Stimulus
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