CD19 Antikörper (AA 485-556)

Produktnummer ABIN724595

Der Kaninchen Polyklonal Anti-CD19-Antikörper wurde für FACS, ELISA, IHC (fro), IHC (p), IF (cc) und IF (p) validiert. Er ist geeignet, CD19 in Proben von Human, Maus, Ratte und Schaf zu detektieren. Es sind 3+ Publikationen verfügbar.

Kurzübersicht für CD19 Antikörper (AA 485-556) (ABIN724595)

Highlights:

• High quality CD19 Primärantikörper for the detection of CD19.
• Reliable product with high standard validation data

Target: CD19 (CD19 Molecule (CD19))

Reaktivität: Human, Maus, Ratte, Schaf

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CD19 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-CD19 Antikörper

Bindungsspezifität: AA 485-556

Kreuzreaktivität: Human, Maus, Ratte, Schaf

Homologie: Cow,Pig,Horse,Guinea Pig

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from rat CD19

Isotyp: IgG

Produktspezifische Information:

What can the CD19 Antibody ABIN724595 be used for?: This polyclonal CD19 Antibody detects CD19. The CD19 Antibody has been validated for various applications and can be used for the detection of CD19 and derivatives by Flow Cytometry, ELISA, Immunohistochemistry (Frozen Sections), Immunohistochemistry (Paraffin-embedded Sections), Immunofluorescence (Cultured Cells), Immunofluorescence (Paraffin-embedded Sections).

What validation data is available for this CD19 Antibody?: The Primärantikörper is referenced in 3 publications and is characterized by a proven, very high reliability. It has currently 4 product images that show its performance in a variety of applications. The product is currently available in 100 μL quantity. CD19 Antibody for the detection of CD19 and derivatives.

What is the function of CD19?: Lymphocytes proliferate and differentiate in response to various concentrations of different antigens. The ability of the B cell to respond in a specific, yet sensitive manner to the various antigens is achieved with the use of low-affinity antigen receptors. This gene encodes a cell surface molecule which assembles with the antigen receptor of B lymphocytes in order to decrease the threshold for antigen receptor-dependent stimulation. [provided by RefSeq, Jul 2008].

Anwendungsinformationen

Applikationshinweise: ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-CD19 Antikörper (ABIN724595)

Takahashi, Ikezumi, Saitoh: "Rituximab protects podocytes and exerts anti-proteinuric effects in rat adriamycin-induced nephropathy independent of B-lymphocytes." in: Nephrology (Carlton, Vic.), Vol. 22, Issue 1, pp. 49-57, (2016) (PubMed).

Reese, Wilson, Huang, Redfield, Zhong, Djamali: "Calcineurin Inhibitor Minimization With Ixazomib, an Investigational Proteasome Inhibitor, for the Prevention of Antibody Mediated Rejection in a Preclinical Model." in: Transplantation, (2015) (PubMed).

Goodwin, Choi, Hsieh, Neugent, Ahn, Hayenga, Singh, Shackelford, Lee, Shulaev, Dhar, Takeda, Kim: "Targeting Hypoxia-Inducible Factor-1α/Pyruvate Dehydrogenase Kinase 1 Axis by Dichloroacetate Suppresses Bleomycin-induced Pulmonary Fibrosis." in: American journal of respiratory cell and molecular biology, Vol. 58, Issue 2, pp. 216-231 (PubMed).

Details zu CD19

Target: CD19 (CD19 Molecule (CD19))

Andere Bezeichnung: CD19

Hintergrund:

Synonyms: AW495831, B-lymphocyte antigen CD19, Differentiation antigen CD19, CD19

Background: Assembles with the antigen receptor of B-lymphocytes in order to decrease the threshold for antigen receptor-dependent stimulation.

Gen-ID: 12478

UniProt: F1LNH2

Pathways: Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung