PP2A alpha/beta Antikörper (AA 205-309) (Biotin)
Kurzübersicht für PP2A alpha/beta Antikörper (AA 205-309) (Biotin) (ABIN723877)
Target
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
-
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Bindungsspezifität
- AA 205-309
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Kreuzreaktivität
- Human, Maus
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Homologie
- Rat,Dog,Cow,Pig,Chicken,Rabbit
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Aufreinigung
- Purified by Protein A.
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Immunogen
- KLH conjugated synthetic peptide derived from human PP-2A
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Isotyp
- IgG
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-
-
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Applikationshinweise
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WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500 -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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-
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Format
- Liquid
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Konzentration
- 1 μg/μL
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Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C for 12 months.
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Haltbarkeit
- 12 months
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- PP2A alpha/beta (PP2A A/B)
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Andere Bezeichnung
- PP2A alpha / beta
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Hintergrund
-
Synonyms: RP-C, PP2Ac, PP2CA, PP2Calpha, Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform, PP2A-alpha, Replication protein C, PPP2CA
Background: PP2A is the major phosphatase for microtubule-associated proteins (MAPs). PP2A can modulate the activity of phosphorylase B kinase casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase. Cooperates with SGOL2 to protect centromeric cohesin from separase-mediated cleavage in oocytes specifically during meiosis I (By similarity). Can dephosphorylate SV4 large T antigen and p53/TP53. Activates RAF1 by dephosphorylating it at 'Ser-259'.
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Gen-ID
- 5515
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UniProt
- P67775
Target
-