Melatonin Receptor 1A Antikörper (AA 201-280)

Produktnummer ABIN723815

Der Kaninchen Polyklonal Anti-Melatonin Receptor 1A-Antikörper wurde für WB, ELISA, FACS, IF (p), IHC (p), IHC (fro) und DB validiert. Er ist geeignet, Melatonin Receptor 1A in Proben von Human, Maus, Rind (Kuh) und Ratte zu detektieren. Es sind 4+ Publikationen verfügbar.

Kurzübersicht für Melatonin Receptor 1A Antikörper (AA 201-280) (ABIN723815)

Target: Melatonin Receptor 1A (MTNR1A)

Reaktivität: Human, Maus, Rind (Kuh), Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Melatonin Receptor 1A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Dot Blot (DB)

Produktdetails anti-Melatonin Receptor 1A Antikörper

Bindungsspezifität: AA 201-280

Kreuzreaktivität: Rind (Kuh), Human, Maus, Ratte

Homologie: Dog,Cow,Sheep,Pig,Chicken,Guinea Pig

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human MTR-1A

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
dot-blot()

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-Melatonin Receptor 1A Antikörper (ABIN723815)

Yang, Tang, Wang, Zhang, Zan: "Melatonin promotes triacylglycerol accumulation via MT2 receptor during differentiation in bovine intramuscular preadipocytes." in: Scientific reports, Vol. 7, Issue 1, pp. 15080, (2019) (PubMed).

Tabecka-Lonczynska, Mytych, Solek, Kulpa, Koziorowski: "New insight on the role of melatonin receptors in reproductive processes of seasonal breeders on the example of mature male European bison (Bison bonasus, Linnaeus 1758)." in: Journal of photochemistry and photobiology. B, Biology, Vol. 173, pp. 84-91, (2017) (PubMed).

Jang, Na, Hong, Lee, Moon, Cho, Park, Lee, Chang, Lee, Ko, Lee, Choi: "Synergistic effect of melatonin and ghrelin in preventing cisplatin-induced ovarian damage via regulation of FOXO3a phosphorylation and binding to the p27Kip1promoter in primordial follicles." in: Journal of pineal research, Vol. 63, Issue 3, (2017) (PubMed).

Wang, Liu, Wu, Ma, Ahmad, Liu, Han, Jiang, Zhang, Yang: "Melatonin suppresses apoptosis and stimulates progesterone production by bovine granulosa cells via its receptors (MT1 and MT2)." in: Theriogenology, Vol. 78, Issue 7, pp. 1517-26, (2012) (PubMed).

Details zu Melatonin Receptor 1A

Target: Melatonin Receptor 1A (MTNR1A)

Andere Bezeichnung: Melatonin Receptor 1A

Hintergrund:

Synonyms: MT1, MEL-1A-R, Melatonin receptor type 1A, Mel1a receptor, MTNR1A

Background: High affinity receptor for melatonin. Likely to mediates the reproductive and circadian actions of melatonin. The activity of this receptor is mediated by pertussis toxin sensitive G proteins that inhibit adenylate cyclase activity.

Gen-ID: 4543

UniProt: P48039