Endothelin 1 Antikörper (Biotin)

Produktnummer ABIN722768

Der Maus Monoklonal anti-Endothelin 1 Antikörper wird verwendet zum Nachweis von Endothelin 1 in Proben von Human und Ratte. Er wurde validiert für WB und IHC (p).

Kurzübersicht für Endothelin 1 Antikörper (Biotin) (ABIN722768)

Target: Endothelin 1 (EDN1)

Reaktivität: Human, Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Endothelin 1 Antikörper ist konjugiert mit Biotin

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: 2C4

Produktdetails anti-Endothelin 1 Antikörper (Biotin)

Kreuzreaktivität: Human, Ratte

Aufreinigung: Purified by Protein G.

Immunogen: KLH conjugated synthetic peptide derived from human Endothelin-1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu Endothelin 1

Target: Endothelin 1 (EDN1)

Andere Bezeichnung: Endothelin-1

Hintergrund:

Synonyms: EDN 1, EDN1, EDN1 protein, Endothelin1, ET 1, ET1,

Background: Endothelins (ET) show potent constrictor activity in vascular and non-vascular smooth muscle. This family of 21-amino acid peptides exists in at least three isoforms - ET-1, ET-2, and ET-3, and is produced in endothelial and epithelial cells. ET's can mediate biological effects in cells and tissues, and have been shown to bind to an ET receptor in the lung, kidney, heart, and liver. Endothelin 1 is expressed in lung, placental stem villi vessels and in cultured placental vascular smooth muscle cells.

Gen-ID: 1906

Pathways: Hormone Transport, Negative Regulation of Hormone Secretion, Regulation of Systemic Arterial Blood Pressure by Hormones, cAMP Metabolic Process, Regulation of Muscle Cell Differentiation, Regulation of G-Protein Coupled Receptor Protein Signaling, Regulation of Cell Size