Rekombinanter NCR1 Antikörper

Produktnummer ABIN7543464

Der Kaninchen Monoklonal Anti-NCR1-Antikörper wurde für FACS und Act validiert. Er ist geeignet, NCR1 in Proben von Maus zu detektieren.

Kurzübersicht für Rekombinanter NCR1 Antikörper (ABIN7543464)

Target: NCR1 (Natural Cytotoxicity Triggering Receptor 1 (NCR1))

Antikörpertyp: Recombinant Antibody

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser NCR1 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Activation (Act)

Klon: 29A1-4

Produktdetails anti-NCR1 Antikörper

Verwendungszweck: Anti-Nkp46 [29A1.4], Rabbit IgG, kappa

Spezifität: This antibody is specific for mouse NKp46-Fc.

Produktmerkmale:

Original Species of Ab: Rat

Original Format of Ab: IgG2a

Aufreinigung: Protein A affinity purified

Immunogen: The original antibody was generated by immunizing rats with mouse NKp46-Fc recombinant protein.

Isotyp: IgG kappa

Anwendungsinformationen

Applikationshinweise: The original format of this antibody was used in an FC analysis to detect NKp46 expression on NK cells and to activate NK in an NK cell stimulation assay (Walzer et al., 2007, PMID: 17360655). This antibody was used as a component of bispecific NKCEs (Natural Killer Cell Engagers) to redirect the cytotoxic activity of NK cells towards human CD20-expressing tumor cells in a transplantable xenogeneic in vivo solid tumor model (Gauthier et al., 2019, PMID: 31155232).

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Details zu NCR1

Target: NCR1 (Natural Cytotoxicity Triggering Receptor 1 (NCR1))

Andere Bezeichnung: Nkp46

Hintergrund: CD335, NK-p46, NKp46, mNKp46, mAR-1, Activating receptor 1, Lymphocyte antigen 94, Natural killer cell p46-related protein, Natural cytotoxicity triggering receptor 1

UniProt: Q8C567

Pathways: Regulation of Leukocyte Mediated Immunity