Rekombinanter Ferritin Antikörper
FE
Reaktivität: Human
IP
Wirt: Kaninchen
Monoclonal
AMB8LK
unconjugated
Recombinant Antibody
-
- Target Alle Ferritin (FE) Antikörper anzeigen
- Ferritin (FE)
- Antikörpertyp
- Recombinant Antibody
-
Reaktivität
- Human
-
Wirt
- Kaninchen
-
Klonalität
- Monoklonal
-
Konjugat
- Dieser Ferritin Antikörper ist unkonjugiert
-
Applikation
- Immunoprecipitation (IP)
- Verwendungszweck
- Anti-Ferritin [AMB8LK], Rabbit IgG, kappa
- Spezifität
- This antibody binds human ferritin. This protein catalyzes the oxidation of ferrous iron(II) to ferric iron(III) and stores iron in a soluble, non-toxic, readily available form. Ferritin is important for iron homeostasis.
- Produktmerkmale
-
Original Species of Ab: Mouse
Original Format of Ab: IgG1
- Aufreinigung
- Protein A affinity purified
- Immunogen
- The original antibody was generated by immunizing female Balb/c mice with ferritin extracted from human spleen cells.
- Klon
- AMB8LK
- Isotyp
- IgG kappa
- Top Product
- Discover our top product FE Primärantikörper
-
anti-Ferritin (FE) antibody
FE Reaktivität: Human WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
-
- Applikationshinweise
- This antibody was capable of immunoprecipitating ferritin (PMID: 6817879). The original antibody binds human ferritin with a binding affinity of Kd= 5.1nM (EP2193147). The thiolated version of this antibody was conjugated to maleimide-activated polylactide nanoparticles (NPs) to generate immunonanoparticles, which may carry drugs to desired overexpressing antigen cells potentially leading to improved drug therapy and reduced systemic adverse effects (PMID: 19835957). Preclinical studies showed that the immunoconjugate with 90Y has 98 % stability over 7 days. A very good pancreatic adenocarcinoma tumor targeting was observed especially with the Bz-DTPA-AMB8LK (PMID: 17383579)
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Konzentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % Proclin 300.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
-
- Target
- Ferritin (FE)
- Andere Bezeichnung
- Ferritin (FE Produkte)
- Hintergrund
- FTMT, FTL, FTH1, Ferritin mitochondrial, B8
- UniProt
- Q8N4E7
- Pathways
- Transition Metal Ion Homeostasis
-
Sie sind hier:
