Rekombinanter Ferritin Antikörper
Kurzübersicht für Rekombinanter Ferritin Antikörper (ABIN7543449)
Target
Alle Ferritin (FE) Antikörper anzeigenAntikörpertyp
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
-
-
Verwendungszweck
- Anti-Ferritin [F11 (HSF102)], Rabbit IgG, kappa
-
Spezifität
-
This antibody binds human ferritin. This protein catalyzes the oxidation of ferrous iron(II) to ferric iron(III) and stores iron in a soluble, non-toxic, readily available form. Ferritin is important for iron homeostasis.
Application Notes original Clone: The binding characterization of this antibody towards human spleen ferritin was done using ELISA. This antibody was also reported to show binding affinity for protein A. Binding of this antibody to ferritin causes antigen-induced conformational changes in the antibody and reduces its affinity for protein A (PMID: 9776583).
-
Produktmerkmale
- This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG2a format, for improved compatibility with existing reagents, assays and techniques.
-
Aufreinigung
- Protein A affinity purified
-
Immunogen
- The original antibody was generated by immunizing female Balb/c mice with ferritin extracted from human spleen cells.
-
Isotyp
- IgG, kappa
-
-
-
-
Applikationshinweise
- Optimal working dilution should be determined by the investigator.
-
Kommentare
-
OriginalSpeciesName: Mouse
OriginalFormat: IgG2a
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Konzentration
- 1 mg/mL
-
Buffer
- PBS with 0.02 % Proclin 300.
-
Konservierungsmittel
- ProClin
-
Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- 4 °C,-20 °C
-
Informationen zur Lagerung
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
-
-
- Ferritin (FE)
-
Andere Bezeichnung
- Ferritin
-
Hintergrund
- FTMT, FTL, FTH1, Ferritin mitochondrial, B8
-
UniProt
- Q8N4E7
-
Pathways
- Transition Metal Ion Homeostasis
Target
-