Rekombinanter FTH1 Antikörper

Produktnummer ABIN7543446

Der Maus Monoklonal anti-FTH1 Antikörper wird verwendet zum Nachweis von FTH1 in Proben von Human. Er wurde validiert für WB, ELISA und IHC.

Kurzübersicht für Rekombinanter FTH1 Antikörper (ABIN7543446)

Target: FTH1 (Ferritin Heavy Chain 1 (FTH1))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser FTH1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Klon: 4C9

Produktdetails anti-FTH1 Antikörper

Verwendungszweck: Anti-Ferritin H [4C9], Mouse IgG1, kappa

Spezifität: This antibody binds human acidic isoferritin. Ferritin is a protein that catalyzes the oxidation of ferrous iron(II) to ferric iron(III) and stores iron in a soluble, non-toxic, readily available form. Ferritin is important for iron homeostasis. Ferritins occur as many isoforms, all of which are composed of various combinations of the two primary subunits, H and L. Acidic isoferritins have high proportions of H subunit.

Produktmerkmale:

Original Species of Ab: Mouse

Original Format of Ab: IgG1

Aufreinigung: Protein A affinity purified

Immunogen: The original antibody was generated by immunizing BALB/c mice with acidic isoferritin (AIF) from primary hepatic carcinoma (PHC) tissues.

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: The binding specificity of this antibody towards acidic isoferritin, basic isoferritin and human liver ferritin was determined using ELISA. This antibody does not cross react with basic isoferritin and human liver ferritin. The binding affinity of the original mouse IgG1 format of this antibody for acidic isoferritin was reported to be Kd= 4.15 nM. This antibody was used for the immunohistochemical staining of liver tissues of primary hepatic carcinoma (PHC)(PMID: 11604110). This antibody can be used for the identification of acidic isoferritins in a western blot (PMID: 12697395).

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Details zu FTH1

Target: FTH1 (Ferritin Heavy Chain 1 (FTH1))

Andere Bezeichnung: Ferritin H

Hintergrund: FTH1, FTHL6, AIF, acidic isoferritin, Ferritin heavy chain, Ferritin H subunit

UniProt: P02794

Pathways: Transition Metal Ion Homeostasis