Rekombinanter Apo-B100 Antikörper
Kurzübersicht für Rekombinanter Apo-B100 Antikörper (ABIN7543445)
Target
Alle Apo-B100 Antikörper anzeigenAntikörpertyp
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Verwendungszweck
- Anti-Apolipoprotein B-100 [MabB9], Mouse IgG2b, kappa
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Spezifität
- This antibody binds human apolipoprotein B (APOB). Apolipoprotein B is a major protein constituent of chylomicrons (apo B-48), LDL (apo B-100) and VLDL (apo B-100). Apo B-100 functions as a recognition signal for the cellular binding and internalization of LDL particles by the apoB/E receptor. It is involved in the metabolism of lipids and is the main protein constituent of lipoproteins such as very low-density lipoprotein (VLDL) and low-density lipoprotein (LDL, the ""bad cholesterol"").
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Produktmerkmale
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Original Species of Ab: Mouse
Original Format of Ab: IgG2b
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Aufreinigung
- Protein A affinity purified
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Immunogen
- The original antibody was generated by immunizing female BALB/c mice intraperitoneally with 20ug of human apo B-100 and dead Salmonella microbes.
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Isotyp
- IgG2b kappa
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Applikationshinweise
- The binding characterization of this antibody towards human APO-B was done using ELISA and immunoblotting. This antibody was also used in a serum assay to determine the quantity of apo-B in a sample using competitive ELISA. This antibody was shown to react with isolated human Apo-B as well as low density lipids but not with high density lipids and lipoprotein-deficient serum (Yoon et al., 1993).
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1 mg/mL
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Buffer
- PBS with 0.02 % Proclin 300.
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
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- Apo-B100 (Apoprotein B100 (Apo-B100))
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Andere Bezeichnung
- Apolipoprotein B-100
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Hintergrund
- APOB, Apolipoprotein B-100, Apo B-100
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UniProt
- P04114
Target
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