Rekombinanter OCT4 Antikörper

Produktnummer ABIN7543402

Dieses Anti-OCT4-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von OCT4 in WB und IHC. Geeignet für Human.

Kurzübersicht für Rekombinanter OCT4 Antikörper (ABIN7543402)

Target: OCT4 (POU5F1) (POU Class 5 Homeobox 1 (POU5F1))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser OCT4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Klon: 41B1

Produktdetails anti-OCT4 Antikörper

Verwendungszweck: Anti-Oct3/4 [41B1], Mouse IgG2b, kappa

Spezifität: The original antibody is specific for OCT3/4. OCT3/4 is a transcription factor that binds to the octamer motif (5'-ATTTGCAT-3'). It forms a trimeric complex with SOX2 or SOX15 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. It is critical for early embryogenesis and for embryonic stem cell pluripotency.

Produktmerkmale:

Original Species of Ab: Mouse

Original Format of Ab: IgG2b

Aufreinigung: Protein A affinity purified

Immunogen: The original antibody was generated by immunizing mice with recombinant protein OCT3/4.

Isotyp: IgG2b kappa

Anwendungsinformationen

Applikationshinweise: The antibody 41B1 and the commercial antibody C-10 were used to stain collagen tumor, dysgerminoma and testicular tissue in immunohistochemistry. Results showed the antibody specificity is comparable to the commercial antibody. Further, the staining intensity of the antibody 41B1 was higher than the commercial antibody (CN113072642A).

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Details zu OCT4

Target: OCT4 (POU5F1) (POU Class 5 Homeobox 1 (POU5F1))

Andere Bezeichnung: Oct3/4

Hintergrund: C-10, KS20.8, POU5F1, Oct4, POU domain, class 5, transcription factor 1, POU domain, class 5, transcription factor 1, Octamer-binding protein 3, Oct-3, Octamer-binding protein 4, Oct-4, Octamer-binding transcription factor 3, OTF-3, CGMCC NO 20779

UniProt: Q01860

Pathways: Stem Cell Maintenance