Rekombinanter OCT4 Antikörper

Produktnummer ABIN7543401

Der Kaninchen Chimeric Anti-OCT4-Antikörper wurde für WB und IHC validiert. Er ist geeignet, OCT4 in Proben von Human zu detektieren.

Kurzübersicht für Rekombinanter OCT4 Antikörper (ABIN7543401)

Target: OCT4 (POU5F1) (POU Class 5 Homeobox 1 (POU5F1))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Chimeric

Konjugat: Dieser OCT4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Klon: 41B1

Produktdetails anti-OCT4 Antikörper

Verwendungszweck: Anti-Oct3/4 [41B1], Rabbit IgG, kappa

Spezifität: The original antibody is specific for OCT3/4. OCT3/4 is a transcription factor that binds to the octamer motif (5'-ATTTGCAT-3'). It forms a trimeric complex with SOX2 or SOX15 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. It is critical for early embryogenesis and for embryonic stem cell pluripotency.

Produktmerkmale:

Original Species of Ab: Mouse

Original Format of Ab: IgG2b

Aufreinigung: Protein A affinity purified

Immunogen: The original antibody was generated by immunizing mice with recombinant protein OCT3/4.

Isotyp: IgG kappa

Anwendungsinformationen

Applikationshinweise: The antibody 41B1 and the commercial antibody C-10 were used to stain collagen tumor, dysgerminoma and testicular tissue in immunohistochemistry. Results showed the antibody specificity is comparable to the commercial antibody. Further, the staining intensity of the antibody 41B1 was higher than the commercial antibody (CN113072642A).

Kommentare:

This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG2b format for improved compatibility with existing reagents assays and techniques.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Details zu OCT4

Target: OCT4 (POU5F1) (POU Class 5 Homeobox 1 (POU5F1))

Andere Bezeichnung: Oct3/4

Hintergrund: C-10, KS20.8, POU5F1, Oct4, POU domain, class 5, transcription factor 1, POU domain, class 5, transcription factor 1, Octamer-binding protein 3, Oct-3, Octamer-binding protein 4, Oct-4, Octamer-binding transcription factor 3, OTF-3, CGMCC NO 20779

UniProt: Q01860

Pathways: Stem Cell Maintenance