Rekombinanter Estrogen Receptor alpha Antikörper

Produktnummer ABIN7543365

Der Kaninchen Chimeric anti-Estrogen Receptor alpha Antikörper wird verwendet zum Nachweis von Estrogen Receptor alpha in Proben von Human. Er wurde validiert für ELISA.

Kurzübersicht für Rekombinanter Estrogen Receptor alpha Antikörper (ABIN7543365)

Target: Estrogen Receptor alpha (ESR1) (Estrogen Receptor 1 (ESR1))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Chimeric

Konjugat: Dieser Estrogen Receptor alpha Antikörper ist unkonjugiert

Applikation: ELISA

Klon: 4E11

Produktdetails anti-Estrogen Receptor alpha Antikörper

Verwendungszweck: Anti-Estrogen receptor [4E11], Rabbit IgG, kappa

Spezifität: The antibody is specific for estrogen receptor ER-α36. The estrogen receptor ER-α36 is an estrogen receptor subtype mainly expressed on the cell membrane, it mediates the non-genomic estrogen signal pathway, and can inhibit the traditional estrogen signal pathway. It plays a vital role in the occurrence and development of diseases. For example its expression level is closely related to some biological indicators of cancer.

Produktmerkmale:

Original Species of Ab: Mouse

Original Format of Ab: IgG2b

Aufreinigung: Protein A affinity purified

Immunogen: The original antibody was generated by immunizing mice with estrogen receptor ER-alpha36.

Isotyp: IgG kappa

Anwendungsinformationen

Applikationshinweise: The antibody specifically recognized ER-α36 protein expressed by SUM159 cells, as confirmed by ELISA analysis (CN107987164).

Kommentare:

This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG2b format for improved compatibility with existing reagents assays and techniques.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Details zu Estrogen Receptor alpha

Target: Estrogen Receptor alpha (ESR1) (Estrogen Receptor 1 (ESR1))

Andere Bezeichnung: Estrogen receptor

Hintergrund: ER, ERα36, ER-α36, hER-α36, ESR1, ER-alpha, NR3A1, Estradiol receptor, Nuclear receptor subfamily 3 group A member 1, ER-alpha Estradiol receptor, Nuclear receptor subfamily 3 group A member 1

UniProt: P03372

Pathways: Nuclear Receptor Transcription Pathway, EGFR Signaling Pathway, Retinoic Acid Receptor Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly