Rekombinanter Histone H4 Antikörper

Produktnummer ABIN7543354

Dieses Anti-Histone H4-Antikörper ist ein Kaninchen Chimeric-Antikörper zur Detektion von Histone H4 in WB, ELISA und Crys. Geeignet für Human.

Kurzübersicht für Rekombinanter Histone H4 Antikörper (ABIN7543354)

Target: Histone H4

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Chimeric

Konjugat: Dieser Histone H4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Crystallization (Crys)

Klon: 1A9D7

Produktdetails anti-Histone H4 Antikörper

Verwendungszweck: Anti-Histone H4 [1A9D7], Rabbit IgG, kappa

Spezifität: The antibody specifically recognizes simultaneous acetylations at K5 and K8 of histone H4. Lysine acetylation of core histones is one of the major posttranslational modifications involved in the control of eukaryotic gene expression.

Produktmerkmale:

Original Species of Ab: Mouse

Original Format of Ab: IgG1

Aufreinigung: Protein A affinity purified

Immunogen: The original antibody was generated by immunizing mice with Histone H4 protein with site-specific acetylations at K5 and K8.

Isotyp: IgG kappa

Anwendungsinformationen

Applikationshinweise: The specificity of the original format of the antibody for histone H4 proteins containing di-acetylation of K5acK8ac was confirmed by ELISA analysis. The antibody detected the histone H4 proteins containing at least the di-acetylation of K5acK8ac western blot analysis. The crystal structure of the complex of di-acetylated histone H4 and 1A9D7 Fab fragment was determined (Handoko et al., 2018, PMID: 30080437).

Kommentare:

This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG format for improved compatibility with existing reagents assays and techniques.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Details zu Histone H4

Target: Histone H4

Hintergrund: H4K5acK8ac, Histone H4 protein,

UniProt: P62805