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Rekombinanter LI Cadherin Antikörper

Dieses Anti-LI Cadherin-Antikörper ist ein Kaninchen Chimeric-Antikörper zur Detektion von LI Cadherin in ELISA und FACS. Geeignet für Human.
Produktnummer ABIN7543348

Kurzübersicht für Rekombinanter LI Cadherin Antikörper (ABIN7543348)

Target

Alle LI Cadherin Antikörper anzeigen
LI Cadherin

Antikörpertyp

Recombinant Antibody

Reaktivität

  • 95
  • 10
  • 8
  • 7
Human

Wirt

  • 57
  • 35
  • 5
Kaninchen

Klonalität

  • 62
  • 31
  • 2
Chimeric

Konjugat

  • 51
  • 7
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser LI Cadherin Antikörper ist unkonjugiert

Applikation

  • 60
  • 43
  • 41
  • 28
  • 20
  • 9
  • 8
  • 7
  • 5
  • 5
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
ELISA, Flow Cytometry (FACS)

Klon

D2111
  • Verwendungszweck

    Anti-Cadherin 17 [D2111], Rabbit IgG, kappa

    Spezifität

    This antibody recognizes the human cadherin 17. Cadherins are calcium-dependent cell adhesion proteins. It is localized on the surfaces of epithelial cells in regions of cell-cell contact known as adherens junctions. They preferentially interact with themselves in a homophilic manner in connecting cells, cadherins may thus contribute to the sorting of heterogeneous cell types.

    Produktmerkmale

    Original Species of Ab: Mouse

    Original Format of Ab: IgG1

    Aufreinigung

    Protein A affinity purified

    Immunogen

    The original antibody was generated by immunizing GP64 transgenic mice with human cadherin 17.

    Isotyp

    IgG kappa
  • Applikationshinweise

    The binding characterization and epitope mapping of this antibody was done using ELISA. This antibody was capable of binding Huh6 cell line (liver cancer) and AGS cells (gastric cancer) in flow cytometry. Cu64 labelled version of this antibody was also used in the PET imaging of AGS transplant mice (JP2017024991).

    Kommentare

    This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format for improved compatibility with existing reagents assays and techniques.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Konzentration

    1 mg/mL

    Buffer

    PBS with 0.02 % Proclin 300.

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
  • Target

    LI Cadherin

    Andere Bezeichnung

    Cadherin 17

    Hintergrund

    Cadherin-17, CDH17, Intestinal peptide-associated transporter HPT-1, Liver-intestine cadherin, LI-cadherin

    UniProt

    Q12864
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