Rekombinanter KRT20 Antikörper
Kurzübersicht für Rekombinanter KRT20 Antikörper (ABIN7543325)
Target
Alle KRT20 Antikörper anzeigenAntikörpertyp
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Verwendungszweck
- Anti-Cytokeratin 20 [10A2], Mouse IgG2a, kappa
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Spezifität
- This antibody binds human cytokeratin 20. Cytokeratins are intermediate filaments found in the intracytoplasmic cytoskeleton of epithelial tissue. There are 19 keratin polypeptides are found in human epithelium. Cytokeratin 20 plays a significant role in maintaining keratin filament organization in intestinal epithelia. When phosphorylated, it plays a role in the secretion of mucin in the small intestine.
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Produktmerkmale
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Original Species of Ab: Mouse
Original Format of Ab: IgG2a
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Aufreinigung
- Protein A affinity purified
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Immunogen
- The original antibody was generated by immunizing female ICR mice with recombinant human CK20 histidine-tagged fusion protein in Freund's complete adjuvant.
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Isotyp
- IgG2a kappa
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Applikationshinweise
- The binding characterization of this antibody was done using ELISA. The affinity constant of the original IgG2a antibody was determined to be 1.92 x 10^9 M^(-1). This antibody was capable of detecting recombinant CK20 protein in a western blot assay. This antibody is similar to commercially available anti-Cytokeratin 20 antibody KS20.8 in staining various human tissues. This antibody was used in the immunohistochemical staining of stomach epithelial tissues and gastric adenocarcinomas (CN113583120).
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1 mg/mL
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Buffer
- PBS with 0.02 % Proclin 300.
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
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- KRT20 (Keratin 20 (KRT20))
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Andere Bezeichnung
- Cytokeratin 20
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Hintergrund
- CK20, CK-20, K20, KRT20, Cytokeratin-20, Keratin-20, Keratin type I cytoskeletal 20 ,Protein IT, CGMCC NO 20764, KS20.8
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UniProt
- P35900
Target
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