Rekombinanter KRT17 Antikörper (AA 410-432)

Produktnummer ABIN7543317

Der Maus Monoklonal Anti-KRT17-Antikörper wurde für IHC und ELISA validiert. Er ist geeignet, KRT17 in Proben von Human zu detektieren.

Kurzübersicht für Rekombinanter KRT17 Antikörper (AA 410-432) (ABIN7543317)

Target: KRT17 (Keratin 17 (KRT17))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser KRT17 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), ELISA

Klon: 4D2

Produktdetails anti-KRT17 Antikörper

Bindungsspezifität: AA 410-432

Verwendungszweck: Anti-Cytokeratin 17 [4D2], Mouse IgG2a, kappa

Spezifität: This antibody is specific for amino acids 410-432 (TIVEEVQDGKVISSREQVHQTTR) of human cytokeratin 17. Cytokeratins are intermediate filaments found in the intracytoplasmic cytoskeleton of epithelial tissue. Cytokeratin 17 regulates the activity of kinases such as PKC and SRC via binding to integrin beta-1 (ITB1) and the receptor of activated protein C kinase 1 (RACK1).

Produktmerkmale:

Original Species of Ab: Mouse

Original Format of Ab: IgG2a

Aufreinigung: Protein A affinity purified

Immunogen: The original antibody was generated by immunizing female BALB/c mice with an immunogenic polypeptide containing amino acids 410-432 (TIVEEVQDGKVISSREQVHQTTR) of human cytokeratin 17 conjugated with KLH.

Isotyp: IgG2a kappa

Anwendungsinformationen

Applikationshinweise: The binding characterization of this antibody to human cytokeratin 8 was done using ELISA. The affinity constant for the original IgG3 antibody was calculated to be 9.6 x 10^(8) M^(-1). This antibody is similar to commercially available anti-Cytokeratin 17 antibody E3 in staining various human tissues. This antibody can be used in the immunohistochemical analysis of esophageal squamous cell carcinoma (CN113278070).

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Details zu KRT17

Target: KRT17 (Keratin 17 (KRT17))

Andere Bezeichnung: Cytokeratin 17

Hintergrund: CK17, CK-17, KRT17, K17, Keratin, type I cytoskeletal 17, Cytokeratin-17, Keratin-17, CGMCC NO 20762, E3

UniProt: Q04695