Rekombinanter NCR1 Antikörper

Produktnummer ABIN7543306

Dieses Anti-NCR1-Antikörper ist ein Kaninchen Chimeric-Antikörper zur Detektion von NCR1 in FACS, IP und IF. Geeignet für Human.

Kurzübersicht für Rekombinanter NCR1 Antikörper (ABIN7543306)

Target: NCR1 (Natural Cytotoxicity Triggering Receptor 1 (NCR1))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Chimeric

Konjugat: Dieser NCR1 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunoprecipitation (IP), Immunofluorescence (IF)

Klon: Bab281

Produktdetails anti-NCR1 Antikörper

Verwendungszweck: Anti-NKp46 [Bab281], Rabbit IgG, kappa

Spezifität: The antibody is specific for human NKp46. The antibody cross-reacts with macaque NK46 but does not cross-react with mouse NKp46. NKp46 is a receptor expressed by NK cells.

Kreuzreaktivität: Makake

Produktmerkmale:

Original Species of Ab: Mouse

Original Format of Ab: IgG1

Aufreinigung: Protein A affinity purified

Immunogen: The original antibody was generated by immunizing Balb/c mice with recombinant human NKp46 protein.

Isotyp: IgG kappa

Anwendungsinformationen

Applikationshinweise: The antibody was used to immunoprecipitate NKp46 Molecules from NK and COS-7 cells (Pessino et al., 1998, PMID 9730896 and Cantoni et al. 1999, PMID: 10049942). NK cells were analyzed for NKp46 surface expression by immunofluorescence and Flow Cytometry analysis using the antibody (Sivori et al., 1999, PMID: 10359120). The antibody binding to NKp46 promoted an increase of cytolytic activity in NK cells (Sivori et al., 1997, PMID: 9314561 and Sivori et al., 1999, PMID: 10359120).

Kommentare:

This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format for improved compatibility with existing reagents assays and techniques.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Details zu NCR1

Target: NCR1 (Natural Cytotoxicity Triggering Receptor 1 (NCR1))

Andere Bezeichnung: NKp46

Hintergrund: Natural cytotoxicity triggering receptor 1, Lymphocyte antigen 94 homolog, NK cell-activating receptor, Natural killer cell p46-related protein, NK-p46, hNKp46, CD335

UniProt: O76036

Pathways: Regulation of Leukocyte Mediated Immunity