Rekombinanter CD7 Antikörper

Produktnummer ABIN7543249

Dieses Anti-CD7-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von CD7 in FACS. Geeignet für Human.

Kurzübersicht für Rekombinanter CD7 Antikörper (ABIN7543249)

Target: CD7

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD7 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS)

Klon: 3A1f

Produktdetails anti-CD7 Antikörper

Verwendungszweck: Anti-CD7 [3A1f], Mouse IgG1, kappa

Spezifität: This antibody binds human CD7. CD7 is expressed on the majority of immature and mature T-lymphocytes, and T cell leukemia. It is also found on natural killer cells, a small subpopulation of normal B cells and on malignant B cells. CD7 is useful in the identification of precursor T cells as well as an important marker for the identification of leukemic T cells.

Produktmerkmale:

Original Species of Ab: Mouse

Original Format of Ab: IgG1

Aufreinigung: Protein A affinity purified

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: The binding affinity of the scFv version of this antibody was determined using surface plasmon resonance. The affinity of the scFv antibody for human CD7 was found to be 1.8 nM. This the scFv version of this antibody was also used in the generation of single-chain Fv (scFv) immunotoxins specific for the T cell-associated antigen CD7 as a novel therapeutic agent for treatment of human T cell malignancies (PMID: 9120282). This antibody was also used in the generation of a therapeutic fusion protein scFvCD7:sTRAIL, designed to induce target antigen-restricted apoptosis in human T-cell tumors. The binding of the fusion protein to CD7 was tested with flow cytometry (PMID: 15833872).

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Details zu CD7

Target: CD7

Andere Bezeichnung: CD7

Hintergrund: GP40, TP41, T-cell antigen CD7, T-cell leukemia antigen, T-cell surface antigen Leu-9, 3aIf

UniProt: P09564

Pathways: Cell-Cell Junction Organization