Rekombinanter CD19 Antikörper

Produktnummer ABIN7543176

Der Maus Monoklonal anti-CD19 Antikörper wird verwendet zum Nachweis von CD19 in Proben von Maus. Er wurde validiert für FACS, IF und ELISA.

Kurzübersicht für Rekombinanter CD19 Antikörper (ABIN7543176)

Target: CD19 (CD19 Molecule (CD19))

Antikörpertyp: Recombinant Antibody

Reaktivität: Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD19 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunofluorescence (IF), ELISA

Klon: MB19-1

Produktdetails anti-CD19 Antikörper

Verwendungszweck: Anti-CD19 [MB19-1], Mouse IgG1, kappa

Spezifität: This antibody recognizes murine MB19-1 (CD19), a transmembrane protein present in B lymphocytes that regulates its activation. It is required for proper differentiation of B-1 cells.

Kreuzreaktivität: Hund

Produktmerkmale:

Original Species of Ab: Mouse

Original Format of Ab: IgA

Aufreinigung: Protein A affinity purified

Immunogen: This antibody was raised by immunising CD19-deficient mice with a cell line of mCD19+ mouse pre-B cells.

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: This clone can be used to detect and analyze the presence of the CD19 transmembrane protein. The specificity towards the protein has been confirmed using ELISA and immunofluorescence (Sato et al., 1996, PMID: 8906812). Additionally, the MB19-1 antibody has been used in several flow cytometry assays. One group used this antibody to determine the differences in CD19 distribution between cells of young and old mice (Yamamoto et al., 2018, PMID: 29625072). Another group used it to differentiate eosinophils from other leukocytes (Vanella et al., 2017, PMID: 27043413). A final group used flow cytometry to determine the fraction of B cells cells in a sample with this antibody (Bedaret et al., 2009, PMID: 19907079).

Kommentare:

This reformatted mouse antibody was made using the variable domain sequences of the original Mouse IgA format, for improved compatibility with existing reagents, assays and techniques.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Details zu CD19

Target: CD19 (CD19 Molecule (CD19))

Andere Bezeichnung: CD19

Hintergrund: B-lymphocyte antigen CD19, Differentiation antigen CD19, B-lymphocyte surface antigen B4, B4, CD19 Molecule, CD19 antigen

UniProt: P25918

Pathways: Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung