Rekombinanter CD20 Antikörper

Produktnummer ABIN7543096

Dieses Anti-CD20-Antikörper ist ein Kaninchen Chimeric-Antikörper zur Detektion von CD20 in FACS, IF und IP. Geeignet für Human.

Kurzübersicht für Rekombinanter CD20 Antikörper (ABIN7543096)

Target: CD20 (MS4A1) (Membrane-Spanning 4-Domains, Subfamily A, Member 1 (MS4A1))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Chimeric

Konjugat: Dieser CD20 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunofluorescence (IF), Immunoprecipitation (IP)

Klon: 2H7

Produktdetails anti-CD20 Antikörper

Verwendungszweck: Anti-CD20 [2H7], Rabbit IgG, kappa

Spezifität: This antibody is specific for CD20, which is expressed by normal and malignant B cells.

Kreuzreaktivität: Pavian, Schimpanse, Gibbon, Marmoset, Owl Monkey, Primate (Semnopithecus)

Produktmerkmale:

Original Species of Ab: Mouse

Original Format of Ab: IgG2b

Aufreinigung: Protein A affinity purified

Immunogen: This antibody was raised by hyperimmunising a C57BL/6 mouse with the Ia- B cell line 6.16 cl. 3.

Isotyp: IgG kappa

Anwendungsinformationen

Applikationshinweise: This antibody has been used in flow cytometry and quantitative immunofluorescence analysis of human peripheral blood mononuclear leukocytes (Yanase et al, 1986).It has also been used to precipitate CD20 from lysates of the Raji human B cell line (Deans et al, 1995). This antibody has been exploited as part of a an avidin-biotin immunoadsorption system to eliminate Daudi lymphoblasts from human bone marrow (Berenson et al, 1986). A mouse-human chimeric version of this antibody effectively mediates antibody-dependent cellular cytotoxicity with human effector cells and complement-dependent cytotoxicity with human complement (Liu et al, 1987).

Kommentare:

This chimeric rabbit antibody was made using the variable domain sequences of the original mouse IgG2b format, for improved compatibility with existing reagents, assays and techniques.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Details zu CD20

Target: CD20 (MS4A1) (Membrane-Spanning 4-Domains, Subfamily A, Member 1 (MS4A1))

Andere Bezeichnung: CD20

Hintergrund: MS4A1, B-lymphocyte antigen CD20, B-lymphocyte surface antigen B1, Bp35, Leukocyte surface antigen Leu-16, Membrane-spanning 4-domains subfamily A member 1, E9PPL6, P19437

UniProt: P11836