Rekombinanter GRIN2B Antikörper

Produktnummer ABIN7543081

Der Kaninchen Chimeric anti-GRIN2B Antikörper (Klon 17) (ABIN7543081) detektiert spezifisch GRIN2B in Crys. Dieser Antikörper reagiert spezifisch mit Proben aus Ratte.

Kurzübersicht für Rekombinanter GRIN2B Antikörper (ABIN7543081)

Target: GRIN2B (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2B (GRIN2B))

Antikörpertyp: Recombinant Antibody

Reaktivität: Ratte

Wirt: Kaninchen

Klonalität: Chimeric

Konjugat: Dieser GRIN2B Antikörper ist unkonjugiert

Applikation: Crystallization (Crys)

Klon: 17

Produktdetails anti-GRIN2B Antikörper

Verwendungszweck: Anti-NMDA Receptor [17], Rabbit IgG, kappa

Spezifität: Reacts specifically with rat GluN2B ATD.

Produktmerkmale:

Original Species of Ab: Mouse

Original Format of Ab: IgG

Aufreinigung: Protein A affinity purified

Immunogen: Monoclonal antibodies that bind rat GluN2B ATD were obtained by immunizing mice with the purified intact GluN1-GluN2B NMDA receptors. IgGs were purified from hybridoma cell culture supernatant by Protein-A Sepharose. Fab fragments have been prepared by papain proteolysis followed by re-chromatographing onto Protein-A Sepharose to remove Fc.

Isotyp: IgG kappa

Anwendungsinformationen

Applikationshinweise: This antibody has been used for the crystallisation of the NMDA receptor in the absence of an allosteric inhibitor at 2.9A (Tajima 2016).

Kommentare:

This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG format, for improved compatibility with existing reagents, assays and techniques.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Details zu GRIN2B

Target: GRIN2B (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2B (GRIN2B))

Andere Bezeichnung: Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2B

Hintergrund: NMDAR, NMDA-R, Glutamate receptor

UniProt: Q00960

Pathways: Response to Growth Hormone Stimulus, Synaptic Membrane, Feeding Behaviour, Regulation of long-term Neuronal Synaptic Plasticity