Rekombinanter EGFR (Nimotuzumab Biosimilar) Antikörper

Produktnummer ABIN7543062

Der Maus Chimeric Anti-EGFR (Nimotuzumab Biosimilar)-Antikörper wurde für BR, FACS und IHC validiert. Er ist geeignet, EGFR (Nimotuzumab Biosimilar) in Proben von Human zu detektieren.

Kurzübersicht für Rekombinanter EGFR (Nimotuzumab Biosimilar) Antikörper (ABIN7543062)

Target: EGFR (Nimotuzumab Biosimilar)

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Maus

Klonalität: Chimeric

Konjugat: Dieser EGFR (Nimotuzumab Biosimilar) Antikörper ist unkonjugiert

Applikation: Blocking Reagent (BR), Flow Cytometry (FACS), Immunohistochemistry (IHC)

Klon: H-R3

Produktdetails anti-EGFR (Nimotuzumab Biosimilar) Antikörper

Verwendungszweck: Anti-EGFR domain III [h-R3 (Nimotuzumab)], Mouse IgG2a, kappa

Spezifität: Binds to human EGFR domain III at a site distinct from antibody 7A7 (Ab00134) (Talavera et al. 2011)

Produktmerkmale:

Original Species of Ab: Human

Original Format of Ab: IgG1

Aufreinigung: Protein A affinity purified

Immunogen: This antibody we generated by humanisation of the murine antibody R3, raised against EGFR purified from placenta membranes and A431 tumors.

Isotyp: IgG2a kappa

Anwendungsinformationen

Applikationshinweise: This antibody binds to human EGFR and inhibits EGF-dependent clonogenic growth of NRK cells and completely blocks EGF stimulated autophosphorylation of the receptor (Fernandez 1992)

Kommentare:

This chimeric mouse antibody was made using the variable domain sequences of the original Human IgG1 format, for improved compatibility with existing reagents, assays and techniques.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Details zu EGFR (Nimotuzumab Biosimilar)

Target: EGFR (Nimotuzumab Biosimilar)

Substanzklasse: Biosimilar

Hintergrund: ERBB-D3, ERBB1, HER1, PIG61, mENA, avian erythroblastic leukemia viral (v-erb-b) oncogene homolog, cell growth inhibiting protein 40, cell proliferation-inducing protein 61, proto-oncogene c-ErbB-1, receptor tyrosine-protein kinase erbB-1, epidermal growth factor

UniProt: P00533