Rekombinanter CD147 Antikörper

Produktnummer ABIN7543035

Der Ratte Monoklonal Anti-CD147-Antikörper wurde für WB, FACS, IHC und IP validiert. Er ist geeignet, CD147 in Proben von Maus zu detektieren.

Kurzübersicht für Rekombinanter CD147 Antikörper (ABIN7543035)

Target: CD147 (BSG) (Basigin (Ok Blood Group) (BSG))

Antikörpertyp: Recombinant Antibody

Reaktivität: Maus

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser CD147 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunoprecipitation (IP)

Klon: OX-114

Produktdetails anti-CD147 Antikörper

Verwendungszweck: Anti-CD147 [OX-114], Rat IgG1, kappa

Spezifität: OX-114 binds to both the 2- and 3-domain isoforms of CD147. CD147 targets monocarboxylate transporters to the plasma membrane, and is involved in spermatogenesis, embryo implantation, neural network fomration and tumor progression. Stimulates production of matrix metalloproteases. Possibly a receptor for oligomannosidic glycans. CD147 found only in vascular endothelium in non-neoplastic regions of the brain whereas it is present in tmour cells but not in proliferating blood vessels in malignant gliomas.

Produktmerkmale:

Original Species of Ab: Rat

Original Format of Ab: IgG1

Aufreinigung: Protein A affinity purified

Immunogen: OX-114 was generated by immunizing rats with recombinant mCD147d0-2rCD4d3+4.

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: This antibody binds mouse CD147, and has been used in FC and IHC-fr analysis to characterise CD147 and detect the cell types on which it is expressed, indicating that CD147 is a lymphocyte activation marker (Paterson, 1987). This antibody failed to give immunoprecipitates from radiolabelled activated T cells.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Details zu CD147

Target: CD147 (BSG) (Basigin (Ok Blood Group) (BSG))

Andere Bezeichnung: CD147

Hintergrund: Basigin, basic immunoglobulin superfamily, HT7 antigen, membrane glycoprotein gp42, gp42, gp-42, OX114, MRC OX-114, MRC OX114

UniProt: P18572

Pathways: S100 Proteine