Rekombinanter CD172b / SIRP beta Antikörper

Produktnummer ABIN7543024

Produktdetails

Target: CD172b / SIRP beta

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Chimeric

Konjugat: Unkonjugiert

Applikation: Flow Cytometry (FACS), ELISA, Surface Plasmon Resonance (SPR)

Verwendungszweck: Anti-CD172b / SIRPB [OX-130], Rabbit IgG, kappa

Spezifität: This antibody recognizes both common alleles of the human activating SIRPβ1 receptor, does not recognize SIRPγ, but cross-reacts with one of the common alleles of the inhibitory human SIRPα receptor.

Produktmerkmale:

Original Species of Ab: Mouse

Original Format of Ab: IgG2b

Aufreinigung: Protein A affinity purified

Immunogen: Recombinant SIRPbeta1 was purified by nickel affinity chromatography and used to immunize mice.

Klon: OX-130

Isotyp: IgG kappa

Anwendungsinformationen

Applikationshinweise: This antibody binds both common alleles of the human activating SIRPβ1 receptor, but ELISA and surface plasmon resonance results have shown that it reacts with one of the two common alleles of SIRPα, potentially yielding different outcomes when this antibody is used in assays from different individuals.

Kommentare:

This chimeric rabbit antibody was made using the variable domain sequences of the original mouse IgG2b format, for improved compatibility with existing reagents, assays and techniques.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Antigendetails

Target: CD172b / SIRP beta

Hintergrund: SIRP-beta-1, Signal-regulatory protein beta-1, CD172 antigen-like family member B

UniProt: O00241