Rekombinanter CD33 (Gemtuzumab Biosimilar) Antikörper

Produktnummer ABIN7542953

Dieses Maus Chimeric-Antikörper erkennt spezifisch CD33 (Gemtuzumab Biosimilar) in FACS und IF. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für Rekombinanter CD33 (Gemtuzumab Biosimilar) Antikörper (ABIN7542953)

Target: CD33 (Gemtuzumab Biosimilar)

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Maus

Klonalität: Chimeric

Konjugat: Dieser CD33 (Gemtuzumab Biosimilar) Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunofluorescence (IF)

Klon: HP67-6

Produktdetails anti-CD33 (Gemtuzumab Biosimilar) Antikörper

Verwendungszweck: Anti-CD33 [hP67.6 (Gemtuzumab)], Mouse IgG1, kappa

Spezifität: Recognises human CD33.

Produktmerkmale:

Original Species of Ab: Human

Original Format of Ab: IgG4

Aufreinigung: Protein A affinity purified

Immunogen: Gemtuzumab was generated by huminization of the murine P67.6 clone, raised against CD33-transfected FMY9S5 cells of human origin. CD33 is a transmembrane receptor expressed on predominantly on cells of the myeloid lineage, but it can also be found on some lymphoid cells.

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: A human IgG4 variant conjugated to derivative of the cytotoxic drug calicheamicin gamma 1, N-acetylcalicheamicin dimethyl hydrazide, has been used as a therapeutic against acute myeloid leukemia. This antibody may also be used in flow cytometry and immunofluorescence.

Kommentare:

This chimeric mouse antibody was made using the variable domain sequences of the original Human IgG4 format, for improved compatibility with existing reagents, assays and techniques.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Details zu CD33 (Gemtuzumab Biosimilar)

Target: CD33 (Gemtuzumab Biosimilar)

Substanzklasse: Biosimilar

Hintergrund: Siglec-3

UniProt: P20138