HHV8 LANA1 Antikörper
Kurzübersicht für HHV8 LANA1 Antikörper (ABIN7540661)
Target
Reaktivität
Wirt
Klonalität
Applikation
Klon
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Hersteller Produkt- Nr.
- mob395-01
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Hersteller
- Rockland
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Verwendungszweck
- Herpesvirus 8 Monoclonal Antibody
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Kreuzreaktivität (Details)
- This antibody reacts with Herpesvirus 8.
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Aufreinigung
- The antibody was clarified from tissue culture supernatant.
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Immunogen
- Anti-Herpesvirus 8 Antibody was produced in rats by repeated immunizations with recombinant protein corresponding to the latent nuclear antigen-1 molecule of HHV8.
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Isotyp
- IgG3
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Applikationshinweise
- Optional[Neutralization_Dilution]: 1:50-1:100
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Kommentare
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Anti-Herpesvirus 8 (RAT) Monoclonal Antibody was tested in IHC-P with positive control Karposi sarcoma tissues. Cellular Localization: Nuclear. The user is advised to validate the use of the products with their tissue specimens prepared and handled in accordance with their laboratory practices. Consult references (Kiernan, 1981: Sheehan & Hrapchak, 1980) for further details on specimen preparation.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Preservative: 0.01 % (w/v) Sodium Azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Informationen zur Lagerung
- Store at 2-8°C. This antibody is suitable for use until the expiration date when stored at 2-8°C. Do not use product after the expiration date printed on vial. If reagents are stored under conditions other than those specified here, they must be verified by the user. Diluted reagents should be used promptly. Unused portions of antibody preparation should be discarded after one day. The presence of precipitate or an unusual odor indicates that the antibody is deteriorating and should not be used.
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- HHV8 LANA1
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Hintergrund
- Herpes, Herpesvirus, HHV8, latent nuclear antigen, LNA, viral gene orf 73,HHV 8 encodes a latent nuclear antigen (LNA), which is the product of the viral gene orf 73. LNA is capable of forming a complex with retinoblastoma susceptibility gene product, which may be related to its oncogenic activity. HHV8 is associated with three different diseases observed in AIDS patients, kaposi's sarcoma, primary effusion lymphoma (which is a rare type of non-Hodgkin lymphoma affecting the body cavities) and multicentric Castleman's disease. HHV 8 is the likely etiological agent of Kaposi's sarcoma.
Target
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