SLC40A1 Antikörper (Internal Region)

Produktnummer ABIN7540602

Hersteller Produkt- Nr.: 600-401-mg1s

Der Kaninchen Polyklonal anti-SLC40A1 Antikörper wird verwendet zum Nachweis von SLC40A1 in Proben von Human. Er wurde validiert für WB, ELISA, IF und FM.

Kurzübersicht für SLC40A1 Antikörper (Internal Region) (ABIN7540602)

Target: SLC40A1 (Solute Carrier Family 40 (Iron-Regulated Transporter), Member 1 (SLC40A1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SLC40A1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Fluorescence Microscopy (FM)

Produktdetails anti-SLC40A1 Antikörper

Bindungsspezifität: Internal Region

Hersteller Produkt- Nr.: 600-401-mg1s

Hersteller: Rockland

Verwendungszweck: SLC40A1 Antibody

Kreuzreaktivität (Details): This affinity purified antibody is directed against human SLC40A1.

Aufreinigung: The antibody was affinity purified from monospecific antiserum by immunoaffinity purification.

Sterilität: Sterile filtered

Immunogen: Anti-SLC40A1 antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to an internal portion of human SLC40A1 conjugated to Keyhole Limpet Hemocyanin (KLH).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

ELISA_Dilution: 1:10,000 - 1:50,000

IF_Microscopy_Dilution: 15 μg/mL

Western_Blot_Dilution: 10 μg/mL

Kommentare:

Anti-SLC40A1 Antibody has been tested in ELISA, WB, and IF.  Expect a band at ~62.5kDa in western blot using appropriate lysates.  Positive control used: Caco-2 lysate in Western Blot and Hep-G2 in Immunofluorescence.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer:

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Stabilizer: None

Preservative: 0.01 % (w/v) Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store vial at -20° C or below prior to opening. This vial contains a relatively low volume of reagent (25 μL). To minimize loss of volume dilute 1:10 by adding 225 μL of the buffer stated above directly to the vial. Recap, mix thoroughly and briefly centrifuge to collect the volume at the bottom of the vial. Use this intermediate dilution when calculating final dilutions as recommended below. Store the vial at -20°C or below after dilution. Avoid cycles of freezing and thawing.

Haltbarkeit: 12 months

Details zu SLC40A1

Target: SLC40A1 (Solute Carrier Family 40 (Iron-Regulated Transporter), Member 1 (SLC40A1))

Andere Bezeichnung: SLC40A1

Hintergrund: Rabbit Anti-SLC40A1 Antibody, Solute Carrier Family 40 Member 1, Solute Carrier Family 11 (Proton-Coupled Divalent Metal Ion Transporters), Member 3, Solute Carrier Family 40 (Iron-Regulated Transporter), Member 1, SLC11A3, IREG1, FPN1, Iron-Regulated Transporter 1, Iron Regulated Gene 1, Ferroportin-1, Ferroportin 1, MSTP079, MST079, HFE4, MTP1, SLC40A1 (Solute Carrier Family 40 Member 1) may be involved in iron export from duodenal epithelial cell and in transfer of iron between maternal and fetal circulation. Mediates iron efflux in the presence of a ferroxidase (hephaestin and/or ceruloplasmin).  Defects in this gene are a cause of hemochromatosis type 4 (HFE4). Diseases associated with SLC40A1 include Hemochromatosis Type 4 and Type 1.  Anti-SLC40A1 Antibody is useful for researchers interested in mineral absorption, insulin receptor recycling, and transmembrane transporter activity.

Gen-ID: 30061

NCBI Accession: NP_055400

UniProt: Q9NP59

Pathways: Transition Metal Ion Homeostasis