ALDH1L1 Antikörper (Internal Region)

Produktnummer ABIN7540558

Hersteller Produkt- Nr.: 600-101-hb6s

Dieses Anti-ALDH1L1-Antikörper ist ein Ziege Polyklonal-Antikörper zur Detektion von ALDH1L1 in WB, IHC, ELISA, IF und FM. Geeignet für Maus. Dieses Primary Antibody wurde in 1 Publikation zitiert.

Kurzübersicht für ALDH1L1 Antikörper (Internal Region) (ABIN7540558)

Target: ALDH1L1 (Aldehyde Dehydrogenase 1 Family, Member L1 (ALDH1L1))

Reaktivität: Maus

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser ALDH1L1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Fluorescence Microscopy (FM)

Produktdetails anti-ALDH1L1 Antikörper

Bindungsspezifität: Internal Region

Hersteller Produkt- Nr.: 600-101-hb6s

Hersteller: Rockland

Verwendungszweck: Aldh1l1 Antibody

Kreuzreaktivität (Details): This affinity purified antibody is directed against mouse Aldh1l1.

Aufreinigung: The product was affinity purified from monospecific antiserum by immunoaffinity purification.

Sterilität: Sterile filtered

Immunogen: Anti-Aldh1l1 antibody was prepared from whole goat serum produced by repeated immunizations with a synthetic peptide corresponding to an internal portion of mouse Aldh1l1 conjugated to Keyhole Limpet Hemocyanin (KLH).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

ELISA_Dilution: 1:10,000-1:50,000

Immunohistochemistry_Dilution: 1:200

IF_Microscopy_Dilution: 15 μg/mL

Western_Blot_Dilution: 1:1000

Kommentare:

Anti-Aldh1l1 Antibody has been tested in WB, IHC, and IF. Expect a band at ~98.7kDa in western blot using appropriate lysates. Positive control used: NIH3T3 and Ms Liver for WB, Ms Liver and Kidney for IHC, and NIH3T3 for IF.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer:

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Stabilizer: None

Preservative: 0.01 % (w/v) Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store vial at -20° C or below prior to opening. This vial contains a relatively low volume of reagent (25 μL). To minimize loss of volume dilute 1:10 by adding 225 μL of the buffer stated above directly to the vial. Recap, mix thoroughly and briefly centrifuge to collect the volume at the bottom of the vial. Use this intermediate dilution when calculating final dilutions as recommended below. Store the vial at -20°C or below after dilution. Avoid cycles of freezing and thawing.

Haltbarkeit: 12 months

Referenzen für anti-ALDH1L1 Antikörper (ABIN7540558)

Hirai, Miwa, Tanaka, Toriumi, Kunii, Shimbo, Sakamoto, Hino, Izumi, Nagaoka, Yabe, Nakamachi, Shioda, Dan, Miyata, Nishito, Suzuki, Miyashita, Tomoda, Hikida, Horiuchi, Itokawa, Arai, Okado: "High-sucrose diets contribute to brain angiopathy with impaired glucose uptake and psychosis-related higher brain dysfunctions in mice." in: Science advances, Vol. 7, Issue 46, pp. eabl6077, (2021) (PubMed).

Details zu ALDH1L1

Target: ALDH1L1 (Aldehyde Dehydrogenase 1 Family, Member L1 (ALDH1L1))

Andere Bezeichnung: Aldh1l1

Hintergrund: Goat Anti-Aldh1l1 Antibody, Cytosolic 10-formyltetrahydrofolate dehydrogenase, 10-FTHFDH, FDH, Aldehyde dehydrogenase family 1 member L1, Fthfd,Aldh1l1, also known as Aldehyde Dehydrogenase 1 Family Member L1, belongs to the aldehyde dehydrogenase family.  This protein catalyzes the conversion of 10-formyltetrahydrofolate, nicotinamide adenine dinucleotide phosphate (NADP+), and water to tetrahydrofolate, NADPH, and carbon dioxide.  Loss of function or expression of this gene is associated with decreased apoptosis, increased cell motility, and cancer progression. Aldh1l1 is cytoplasmic. Diseases associated with ALDH1L1 include Methanol Poisoning and Pilocytic Astrocytoma.  Anti-Aldh1l1 Antibody is useful for researchers interested in Apoptosis Research, Metabolism Research, and Cancer research.

Gen-ID: 107747

NCBI Accession: NP_081682

UniProt: Q8R0Y6