CBX1 Antikörper

Produktnummer ABIN7540518

Hersteller Produkt- Nr.: 200-401-v35

Der Kaninchen Polyklonal Anti-CBX1-Antikörper wurde für WB, ChIP und FM validiert. Er ist geeignet, CBX1 in Proben von Human zu detektieren.

Kurzübersicht für CBX1 Antikörper (ABIN7540518)

Target: CBX1 (Chromobox Homolog 1 (CBX1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CBX1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Chromatin Immunoprecipitation (ChIP), Fluorescence Microscopy (FM)

Produktdetails anti-CBX1 Antikörper

Hersteller Produkt- Nr.: 200-401-v35

Hersteller: Rockland

Verwendungszweck: HP1 alpha, beta, gamma Antibody

Kreuzreaktivität (Details): Cross-reactivity with HP1 α, β, G from species other than human has not been determined.

Aufreinigung: Anti-HP1 alpha, beta, gamma Antibody was purified by Protein G chromatography.

Sterilität: Sterile filtered

Immunogen: Anti-HP1 alpha, beta, g Antibody was produced in rabbits by repeated immunization with a full length recombinant protein of human HP1 beta. The antibody also recognizes the alpha and gamma isoforms.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

ChIP_Dilution: 4 μg/ChIP

IF_Microscopy_Dilution: 1:500

Western_Blot_Dilution: 1:1,000

Kommentare:

Anti-HP1 α, β, g Antibody is tested in Western blot and suitable for Chromatin Immunoprecipitation and Immunofluorescence. Specific conditions for reactivity should be optimized by the end user.  Expect a band approximately 20 kDa (bands for the alpha, beta, and gamma isoforms are slightly different) in the appropriate cell lysate or extract.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer:

Buffer: 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride, pH 7.2

Stabilizer: None

Preservative: 0.05 % (w/v) Sodium Azide and 0.05 % ProClin 300

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Haltbarkeit: 12 months

Details zu CBX1

Target: CBX1 (Chromobox Homolog 1 (CBX1))

Andere Bezeichnung: CBX1

Hintergrund: Chromobox protein homolog 1, HP1Hsbeta, Heterochromatin protein 1 homolog beta, HP1-beta, Heterochromatin protein p25, M31, Modifier 1 protein, p25 beta,HP1 alpha, beta and gamma (UniProt/Swiss-Prot entry P45973, P83916 and Q13185) are components of heterochromatin. They recognize and bind histone H3 tails methylated at 'Lys-9', leading to epigenetic repression of transcription. HP1 alpha, beta and gamma also interact with lamin B receptor (LBR), thereby contributing to the association of heterochromatin with the innernuclear membrane. Anti-HP1 α, β, g Antibody is ideal for research in Chromatin Remodeling and Epigenetics.

Gen-ID: 10951

NCBI Accession: NP_001120700

UniProt: P83916