FGF13 Antikörper (AA 2-18) (PE)

Produktnummer ABIN7540508

Hersteller Produkt- Nr.: 200-308-w62

Produktdetails anti-FGF13 Antikörper (PE)

Target: FGF13 (Fibroblast Growth Factor 13 (FGF13))

Bindungsspezifität: AA 2-18

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser FGF13 Antikörper ist konjugiert mit PE

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Hersteller Produkt- Nr.: 200-308-w62

Hersteller: Rockland

Verwendungszweck: FGFA/FHFA (pan) Antibody Phycoerythrin

Kreuzreaktivität (Details): BLAST analysis suggests that it is 94 % identical to mouse, 100 % identical to rat and >80 % identical to FGF12A/FHF1A, FGF14A/FHF4A, and FGF11A/FHF3A.

Aufreinigung: Anti-FGFA/FHFA (pan) Antibody was purified from concentrated tissue culture supernate by Protein G chromatography.

Sterilität: Sterile filtered

Immunogen: Anti-FGFA/FHFA (pan) Antibody was produced by repeated immunization of mice with a synthetic peptide containing amino acids 2-18 of human FHF2A.

Klon: S235-22

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise:

ELISA_Dilution: 1:10,000

Immunohistochemistry_Dilution: User Optimized

Western_Blot_Dilution: 1:1000

Kommentare:

Anti-FGFA/FHFA (pan) R-PE Conjugated Antibody is tested for Western Blots, Immunohistochemistry and Immunocytochemistry. Expect a band approximately ~30 kDa on specific lysates or tissues. Does not cross react with FGF13B/FHF2B. Will cross react with FGF12A/FHF1A and FGF14A/FHF4A. Specific conditions for reactivity should be optimized by the end user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer:

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Stabilizer: 50 % (v/v) Glycerol

Preservative: 0.1 % (w/v) Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store vial at 4° C prior to opening. Dilute only prior to immediate use. This product is stable at 4° C as an undiluted liquid. Use subdued lighting during handling and incubation of cells prior to analysis. Store reagent in the dark. DO NOT FREEZE.

Haltbarkeit: 12 months

Details zu FGF13

Target: FGF13 (Fibroblast Growth Factor 13 (FGF13))

Andere Bezeichnung: FGF13 (FGF13 Produkte)

Hintergrund: Acidic fibroblast growth factor, AFGF, Beta endothelial cell growth factor, Fibroblast growth factor homologous factor 2A, Fibroblast growth factor 13A, FGF13A, Beta-endothelial cell growth factor, ECGF, ECGFA antibody, ECGFB, FHF-2, FHF2, FHF13, Fibroblast growth factor homologous factor 2, Fibroblast growth factor 13,FGF13(Fibroblast growth factor 13), also called FHF2 is a protein that in humans is encoded by the FGF13 gene. The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF13is a large gene, extending over approximately 200 kb in Xq26.3, and contains at least 7 exons. By cytogenetic, FISH, and database analysis, Gecz et al. (1999) localized the FGF13 gene within a 400-kb duplication interval on chromosome Xq26.3. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion. Other areas of interests and use for researchers include cancer, borjeson-forssman-lehmann syndrome, regulation of actin cytoskeleton pathways, apoptosis, GPCR pathways, TGF-Beta pathways, and Rho family GTPase pathways. This gene is located to a region associated with Borjeson-Forssman-Lehmann syndrome (BFLS), a syndromal X-linked mental retardation, which suggests it may be a candidate gene for familial cases of the BFL syndrome. The function of this gene has not yet been determined. Two alternatively spliced transcripts encoding different isoforms have been described for this gene.

Gen-ID: 2258

UniProt: Q92913

Pathways: Regulation of Cell Size