ITGA5 Antikörper (PE)

Produktnummer ABIN7540446

Der Maus Monoklonal Anti-ITGA5-Antikörper wurde für FACS validiert. Er ist geeignet, ITGA5 in Proben von Human und Non-Human Primate zu detektieren.

Kurzübersicht für ITGA5 Antikörper (PE) (ABIN7540446)

Target: ITGA5 (Integrin, alpha 5 (ITGA5))

Reaktivität: Human, Non-Human Primate

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser ITGA5 Antikörper ist konjugiert mit PE

Applikation: Flow Cytometry (FACS)

Klon: SAM1

Produktdetails anti-ITGA5 Antikörper (PE)

Verwendungszweck: Anti-Hu CD49e PE

Spezifität: The mouse monoclonal antibody SAM1 recognizes an extracellular epitope of CD49e (integrin 5 alpha), a transmembrane glycoprotein expressed on thymocytes, early and activated B cells, monocytes, NK cells, dendritic cells, osteoblast and endothelial cells.

Aufreinigung: Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

Immunogen: U937 cells

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 10⁶ cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.

Details zu ITGA5

Target: ITGA5 (Integrin, alpha 5 (ITGA5))

Andere Bezeichnung: CD49e

Hintergrund:

NCBI Full Gene Name: integrin subunit alpha 5

Description: CD49e (VLA5 alpha) is a type I transmembrane glycoprotein of the integrin alpha subclass (intergrin 5 alpha), expressed on thymocytes, early and activated B cells, monocytes, NK cells, dendritic cells, osteoblast and endothelial cells. It binds to RGD sequence in fibronectin and to neural adhesion molecule L1. CD49e interactions are important for maintaining the integrity of the endothelial monolayer, as well as it is involved in monocyte migration, T cell costimulation, regulation of cell survival, and other.

Other names: VLA5 alpha, integrin 5 alpha, FNRA

Gene name: ITGA5

Gen-ID: 3678

UniProt: P08648

Pathways: Integrin Complex