SIGLEC9 Antikörper (APC)

Produktnummer ABIN7540435

Dieses Anti-SIGLEC9-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von SIGLEC9 in FACS. Geeignet für Human.

Kurzübersicht für SIGLEC9 Antikörper (APC) (ABIN7540435)

Target: SIGLEC9 (Sialic Acid Binding Ig-Like Lectin 9 (SIGLEC9))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser SIGLEC9 Antikörper ist konjugiert mit APC

Applikation: Flow Cytometry (FACS)

Klon: K8

Produktdetails anti-SIGLEC9 Antikörper (APC)

Verwendungszweck: Anti-Hu CD329 APC

Spezifität: The mouse monoclonal antibody K8 recognizes an extracellular epitope of CD239, a type I transmembrane glycoprotein expressed above all on monocytes, neutrophils, and a minor population of CD16+CD56- cells.

Aufreinigung: Purified antibody is conjugated with activated allophycocyanin (APC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

Immunogen: recombinant CD329-Hu IgGFc fusion protein

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 10⁶ cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.

Details zu SIGLEC9

Target: SIGLEC9 (Sialic Acid Binding Ig-Like Lectin 9 (SIGLEC9))

Andere Bezeichnung: CD329

Hintergrund:

NCBI Full Gene Name: sialic acid binding Ig like lectin 9

Description: CD329 is a type I transmembrane glycoprotein of siglec family, which contains intracellular ITIM motif, and a SLAM-like motif, that acts as a docking site for SAP. CD329 can regulate TCR signaling by recruitment of SHP-1, which results in down-regulation of TCR-based gene transcription. It is expressed above all on monocytes, neutrophils, and a minor population of CD16+CD56- cells, weaker expression is detectable in some B cells, NK cells, and T cells.

Other names: SIGLEC9

Gene name: SIGLEC9

Gen-ID: 27180

UniProt: Q9Y336