GPR77 Antikörper (APC)

Produktnummer ABIN7540411

Dieses Anti-GPR77-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von GPR77 in FACS. Geeignet für Human und Non-Human Primate.

Kurzübersicht für GPR77 Antikörper (APC) (ABIN7540411)

Target: GPR77 (G Protein-Coupled Receptor 77 (GPR77))

Reaktivität: Human, Non-Human Primate

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser GPR77 Antikörper ist konjugiert mit APC

Applikation: Flow Cytometry (FACS)

Klon: 1D9-M12

Produktdetails anti-GPR77 Antikörper (APC)

Verwendungszweck: Anti-Hu C5aR2 APC

Spezifität: The mouse monoclonal antibody 1D9-M12 recognizes an extracellular epitope on C5aR2 (C5L2), a C5a complement receptor, which is coexpressed with C5aR1 (CD88) in neutrophils, as well as e.g. in mast cells, astrocytes, or macrophages.

Aufreinigung: Purified antibody is conjugated with activated allophycocyanin (APC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

Immunogen: L1.2 cells transfected with human C5aR2

Isotyp: IgG2a kappa

Anwendungsinformationen

Applikationshinweise: Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 10⁶ cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.

Details zu GPR77

Target: GPR77 (G Protein-Coupled Receptor 77 (GPR77))

Andere Bezeichnung: C5aR2

Hintergrund:

NCBI Full Gene Name: complement component 5a receptor 2

Description: C5aR2, also known as C5L2, is one of two receptors for C5a (anaphylatoxin). It is coexpressed with C5aR1 (CD88) in neutrophils, as well as e.g. in mast cells, astrocytes, or macrophages, and seems to have both pro-inflammatory and anti-inflammatory roles, depending on circumstances. Unlike CD88, C5aR2 is not coupled to G-protein, thus the modulatory role is more likely.

Other names: C5L2, GPR77, GPF77

Gene name: C5AR2

Gen-ID: 27202

UniProt: Q9P296