Rekombinanter CD8 Antikörper (Extracellular Domain)
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- Target Alle CD8 Antikörper anzeigen
- CD8
- Antikörpertyp
- Recombinant Antibody
- Fragment
- single-domain Antibody (sdAb)
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Bindungsspezifität
- Extracellular Domain
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Reaktivität
- Human
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Wirt
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Alpaca
- Expressionssystem
- E.coli
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Klonalität
- Monoklonal
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Konjugat
- Dieser CD8 Antikörper ist unkonjugiert
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Applikation
- Flow Cytometry (FACS), Immunofluorescence (IF), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (fixed cells) (IF/ICC)
- Verwendungszweck
- Anti-CD8 (Human) LIMAAbody® is a carefully developed and validated polyclonal nanobody (single-domain antibody) binding to human CD8 highly suitable for tissue stainings.
- Marke
- LIMAAbody®
- Spezifität
- Detects endogenous levels of total human CD8 alpha protein.
- Kreuzreaktivität (Details)
- not analysed
- Produktmerkmale
- VHH protein tag: C-terminal (6x) His-Tag
- Aufreinigung
- Affinity-purified antibody fragment.
- Immunogen
- Recombinant protein containing the extracellular domain of human CD8 protein.
- Klon
- 3ALB177
- Top Product
- Discover our top product CD8 Primärantikörper
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anti-CD8 (CD8) (AA 51-150) antibody
CD8 Reaktivität: Human, Maus, Ratte FACS, IHC (fro), WB, ELISA, IHC (p), IF (p), IF (cc) Wirt: Kaninchen Polyclonal unconjugated
anti-CD8 (CD8) antibody (PE)CD8 Reaktivität: Human FACS Wirt: Maus Monoclonal MEM-31 PE
anti-CD8 (CD8) (AA 22-187) antibodyCD8 Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-CD8 (CD8) antibodyCD8 Reaktivität: Human FACS, IP, MS Wirt: Maus Monoclonal MEM-31 unconjugated
anti-CD8 (CD8) antibody (Biotin)CD8 Reaktivität: Human FACS, IP Wirt: Maus Monoclonal MEM-31 Biotin
anti-CD8 (CD8) antibody (FITC)CD8 Reaktivität: Human FACS Wirt: Maus Monoclonal MEM-31 FITC
anti-CD8 (CD8) antibodyCD8 Reaktivität: Human IHC, IP, WB, ELISA Wirt: Kaninchen Monoclonal 3C3 unconjugated Recombinant Antibody
anti-CD8 (CD8) antibody (PerCP)CD8 Reaktivität: Human FACS Wirt: Maus Monoclonal MEM-31 PerCP
anti-CD8 (CD8) antibody (APC)CD8 Reaktivität: Human FACS Wirt: Maus Monoclonal MEM-31 APC
anti-CD8 (CD8) antibody (PE)CD8 Reaktivität: Cat FACS Wirt: Maus Monoclonal fCD8 PE
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- Applikationshinweise
- Immunofluorescence: 10 μg/mL (frozen sections), 10 μg/mL (cell culture), 20 μg/mL (wholemount), 10 μg/mL (FACS)
- Kommentare
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VHH protein tag: C-terminal (6x) His-Tag
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- PBS, pH 7.4, 0.02% sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Do not freeze.
- Lagerung
- 4 °C
- Informationen zur Lagerung
- Upon receipt store at 4°C. Stable for 6 months. Do not freeze.
- Haltbarkeit
- 6 months
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- Target
- CD8
- Andere Bezeichnung
- CD8 (CD8 Produkte)
- Hintergrund
- CD8, known as Cluster of Differentiation 8, forms a disulphide-linked heterodimer comprising unrelated α and β subunits. Each subunit, characterized as a glycoprotein, is structured with a single extracellular Ig-like domain, a polypeptide linker, a transmembrane component, and a concise cytoplasmic tail. Within T cells, CD8 serves as the co-receptor alongside the T cell receptor (TCR). These distinct structures collaboratively identify the Antigen-Major Histocompatibility Complex (MHC). Specifically, the interaction occurs between the Ig-like domain of CD8α and the α3-domain of the MHC class I molecule. CD8 plays a pivotal role in ensuring the specificity of the TCR-antigen interaction, extending the duration of contact between the T cell and the antigen-presenting cell. Moreover, the α chain of CD8 recruits the tyrosine kinase Lck, an indispensable component for initiating T cell activation .
- Molekulargewicht
- 26 kDa
- NCBI Accession
- NP_001759
- UniProt
- P01732
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