OCT4 Antikörper (AA 136-360)
Kurzübersicht für OCT4 Antikörper (AA 136-360) (ABIN7539743)
Target
Alle OCT4 (POU5F1) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 136-360
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Verwendungszweck
- POU5F1 Antibody
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Aufreinigung
- Purified antibody
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Immunogen
- Purified recombinant fragment of human POU5F1 (AA: 136-360) expressed in E. Coli.
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Isotyp
- IgG1
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Applikationshinweise
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ELISA: 1/10000
FCM: 1/200 - 1/400
ICC: 1/50 - 1/200
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- OCT4 (POU5F1) (POU Class 5 Homeobox 1 (POU5F1))
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Andere Bezeichnung
- POU5F1
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Hintergrund
- This gene encodes a transcription factor containing a POU homeodomain that plays a key role in embryonic development and stem cell pluripotency. Aberrant expression of this gene in adult tissues is associated with tumorigenesis. This gene can participate in a translocation with the Ewing's sarcoma gene on chromosome 21, which also leads to tumor formation. Alternative splicing, as well as usage of alternative AUG and non-AUG translation initiation codons, results in multiple isoforms. One of the AUG start codons is polymorphic in human populations. Related pseudogenes have been identified on chromosomes 1, 3, 8, 10, and 12.
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Molekulargewicht
- 38.5 kDa
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UniProt
- Q01860
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Pathways
- Stem Cell Maintenance
Target
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