CD160 Antikörper (AA 25-155)

Produktnummer ABIN7539709

Der Maus Monoklonal Anti-CD160-Antikörper wurde für FACS und ELISA validiert. Er ist geeignet, CD160 in Proben von Human zu detektieren.

Kurzübersicht für CD160 Antikörper (AA 25-155) (ABIN7539709)

Target: CD160

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD160 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), ELISA

Klon: 1D4A4

Produktdetails anti-CD160 Antikörper

Bindungsspezifität: AA 25-155

Verwendungszweck: CD160 Antibody

Aufreinigung: Purified antibody

Immunogen: Purified recombinant fragment of human CD160 (AA: 25-155) expressed in E. Coli.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise:

ELISA: 1/10000

FCM: 1/200 - 1/400

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Details zu CD160

Target: CD160

Andere Bezeichnung: CD160

Hintergrund: CD160 is an 27 kDa glycoprotein which was initially identified with the monoclonal antibody BY55. Its expression is tightly associated with peripheral blood NK cells and CD8 T lymphocytes with cytolytic effector activity. The cDNA sequence of CD160 predicts a cysteine-rich, glycosylphosphatidylinositol-anchored protein of 181 amino acids with a single Ig-like domain weakly homologous to KIR2DL4 Molecule. CD160 is expressed at the cell surface as a tightly disulfide-linked multimer. RNA blot analysis revealed CD160 mRNAs of 1.5 and 1.6 kb whose expression was highly restricted to circulating NK and T cells, spleen and small intestine. Within NK cells CD160 is expressed by CD56dimCD16+ cells whereas among circulating T cells its expression is mainly restricted to TCRgd bearing cells and to TCRab+CD8brightCD95+CD56+CD28-CD27-cells. In tissues, CD160 is expressed on all intestinal intraepithelial lymphocytes. CD160 shows a broad specificity for binding to both classical and nonclassical MHC class I molecules.

Molekulargewicht: 19.8 kDa

Gen-ID: 11126

UniProt: O95971