FOXP3 Antikörper

Produktnummer ABIN7539628

Der Maus Monoklonal anti-FOXP3 Antikörper wird verwendet zum Nachweis von FOXP3 in Proben von Human und Maus. Er wurde validiert für IHC, ELISA und ICC.

Kurzübersicht für FOXP3 Antikörper (ABIN7539628)

Target: FOXP3 (Forkhead Box P3 (FOXP3))

Reaktivität: Human, Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser FOXP3 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC)

Klon: 2A11G9

Produktdetails anti-FOXP3 Antikörper

Verwendungszweck: Foxp3 Antibody

Aufreinigung: Ascitic fluid

Immunogen: Purified recombinant fragment of human Foxp3 expressed in E. Coli.

Anwendungsinformationen

Applikationshinweise:

ELISA: 1/10000

ICC: 1/200 - 1/1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Details zu FOXP3

Target: FOXP3 (Forkhead Box P3 (FOXP3))

Andere Bezeichnung: Foxp3

Hintergrund: The transcription factor Foxp family includes Foxp1, Foxp2, and Foxp3. The Foxp3 (50KDa)plays a key role in CD4(+) CD25(+) regulatory T cell function and represents a specific marker for these cells. Despite its strong association with regulatory T cell function, in humans little is known about the frequency of CD4(+) CD25(+) cells that express FOXP3 protein nor the distribution of these cells in vivo. FOXP3 may be a master regulatory gene and a more specific marker of regulatory T cells than other T cells.

UniProt: Q9BZS1

Pathways: Chromatin Binding, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation